FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term proteasomal protein catabolic process ID (Ontology) GO:0010498 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
Also Known As "proteasome-mediated protein catabolic process" ; "proteasome-mediated protein catabolism"
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       7
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 proteasomal protein catabolic process (all annotations which use CV term, excluding "NOT" statements)       7
     involved_in | proteasomal protein catabolic process       7
Spanning Tree (Parents/Children)
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proteolysis
 |__proteolysis involved in protein catabolic process__
macromolecule catabolic process                        |
 |__protein catabolic process__________________________|
protein metabolic process                              |
 |__protein catabolic process__________________________|
protein catabolic process                              |
 |__proteolysis involved in protein catabolic process__|
                                                       proteasomal protein catabolic process  314 rec.
                                                        |__EGAD pathway
                                                        |__ERAD pathway 46 rec.
                                                        |   |__maintenance of unfolded protein involved in ERAD pathway
                                                        |   |__regulation of ERAD pathway(+) 4 rec.
                                                        |   |__retrograde protein transport, ER to cytosol(+) 4 rec.
                                                        |   |__ubiquitin-dependent glycoprotein ERAD pathway(+) 3 rec.
                                                        |__proteasomal ubiquitin-independent protein catabolic process 1 rec.
                                                        |__proteasome-mediated ubiquitin-dependent protein catabolic process 270 rec.
                                                        |   |__anaphase-promoting complex-dependent catabolic process(+) 19 rec.
                                                        |   |__cytoplasm protein quality control by the ubiquitin-proteasome system
                                                        |   |__mitochondria-associated ubiquitin-dependent protein catabolic process
                                                        |   |__negative regulation of transcription by transcription factor catabolism
                                                        |   |__nuclear protein quality control by the ubiquitin-proteasome system(+) 1 rec.
                                                        |   |__regulation of proteasomal ubiquitin-dependent protein catabolic process(+) 58 rec.
                                                        |   |__ribosome-associated ubiquitin-dependent protein catabolic process(+) 3 rec.
                                                        |   |__SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(+) 68 rec.
                                                        |   |__stress-induced homeostatically regulated protein degradation pathway
                                                        |   |__ubiquitin-dependent protein catabolic process via the C-end degron rule pathway 1 rec.
                                                        |   |__ubiquitin-dependent protein catabolic process via the N-end rule pathway 5 rec.
                                                        |__regulation of proteasomal protein catabolic process 68 rec.
                                                            |__negative regulation of proteasomal protein catabolic process(+) 15 rec.
                                                            |__positive regulation of proteasomal protein catabolic process(+) 52 rec.
                                                            |__regulation of ERAD pathway(+) 4 rec.
                                                            |__regulation of proteasomal ubiquitin-dependent protein catabolic process(+) 58 rec.
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Is a protein catabolic process
proteolysis involved in protein catabolic process
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Synonyms
  • "proteasome-mediated protein catabolic process" EXACT
    "proteasome-mediated protein catabolism" EXACT
Secondary IDs
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