FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term vascular endothelial growth factor signaling pathway ID (Ontology) GO:0038084 (Gene Ontology)
Definition The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.[ PubMed:17470632 ]
Also Known As "vascular endothelial growth factor signalling pathway" ; "VEGF signaling" ; "VEGF-activated signaling pathway"
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enzyme-linked receptor protein signaling pathway
 |__cell surface receptor protein tyrosine kinase signaling pathway___
cellular response to growth factor stimulus                           |
 |__cellular response to vascular endothelial growth factor stimulus__|
                                                                      vascular endothelial growth factor signaling pathway
                                                                       |__positive regulation of cell migration by vascular endothelial growth factor signaling pathway
                                                                       |   |__positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway
                                                                       |   |__positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
                                                                       |__regulation of vascular endothelial growth factor signaling pathway
                                                                       |   |__negative regulation of vascular endothelial growth factor signaling pathway
                                                                       |   |__positive regulation of vascular endothelial growth factor signaling pathway
                                                                       |__VEGF-activated neuropilin signaling pathway
                                                                       |   |__VEGF-activated neuropilin signaling pathway involved in axon guidance
                                                                       |__VEGF-activated platelet-derived growth factor receptor signaling pathway
                                                                           |__positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway
                                                                           |__positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
                                                                           |__VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway
                                                                           |__VEGF-activated platelet-derived growth factor receptor-beta signaling pathway
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Is a cell surface receptor protein tyrosine kinase signaling pathway
Part of cellular response to vascular endothelial growth factor stimulus
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Synonyms
  • "vascular endothelial growth factor signalling pathway" EXACT
    "VEGF signaling" EXACT
    "VEGF-activated signaling pathway" EXACT
Secondary IDs
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