FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term apical junction complex ID (Ontology) GO:0043296 (Gene Ontology)
Definition A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.[ PubMed:12525486 PubMed:15196556 ]
Also Known As "apical cell junction complex" ; "apical junction"
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Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       7
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 apical junction complex (all annotations which use CV term, excluding "NOT" statements)       7
     colocalizes_with | apical junction complex       1
     is_active_in | apical junction complex       4
     located_in | apical junction complex       3
Spanning Tree (Parents/Children)
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  anchoring junction
   |__cell-cell junction
       |__apical junction complex  139 rec.
           |__bicellular tight junction 2 rec.
           |   |__host-symbiont bicellular tight junction
           |__septate junction 97 rec.
           |   |__pleated septate junction 13 rec.
           |   |__smooth septate junction 17 rec.
           |__subapical complex 11 rec.
           |__zonula adherens 33 rec.
               |__puncta adhaerentia
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Is a cell-cell junction
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Synonyms
  • "apical cell junction complex" EXACT
    "apical junction" EXACT
Secondary IDs
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