FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term T-helper 1 cell differentiation ID (Ontology) GO:0045063 (Gene Ontology)
Definition The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
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CD4-positive, alpha-beta T cell differentiation involved in immune response
 |__T-helper cell differentiation_________________________________________________________________________________________
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains  |
 |__T-helper 1 type immune response________________________________________________________________________________________|
                                                                                         T-helper 1 cell differentiation
                                                                                          |__regulation of T-helper 1 cell differentiation
                                                                                          |   |__negative regulation of T-helper 1 cell differentiation
                                                                                          |   |__positive regulation of T-helper 1 cell differentiation
                                                                                          |__T-helper 1 cell lineage commitment
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Is a T-helper cell differentiation
Part of T-helper 1 type immune response
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Synonyms
  • "T-helper 1 cell development" RELATED
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