FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of cell differentiation ID (Ontology) GO:0045596 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
Also Known As "down regulation of cell differentiation" ; "down-regulation of cell differentiation" ; "downregulation of cell differentiation"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       4
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 Genes
 negative regulation of cell differentiation (all annotations which use CV term, excluding "NOT" statements)       4
     involved_in | negative regulation of cell differentiation       4
Spanning Tree (Parents/Children)
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cell differentiation
 |__regulation of cell differentiation____________
negative regulation of biological process         |
 |__negative regulation of cellular process_______|
 |__negative regulation of developmental process__|
regulation of developmental process               |
 |__regulation of cell differentiation____________|
 |__negative regulation of developmental process__|
regulation of cellular process                    |
 |__regulation of cell differentiation____________|
 |__negative regulation of cellular process_______|
                                                  negative regulation of cell differentiation  97 rec.
                                                   |__maintenance of animal organ identity
                                                   |   |__maintenance of kidney identity
                                                   |__maintenance of imaginal histoblast diploidy 1 rec.
                                                   |__maintenance of plant organ identity
                                                   |   |__maintenance of floral organ identity
                                                   |__negative regulation of antipodal cell differentiation
                                                   |__negative regulation of cardiac endothelial to mesenchymal transition
                                                   |__negative regulation of cardiocyte differentiation 5 rec.
                                                   |   |__negative regulation of cardiac cell fate specification(+) 4 rec.
                                                   |   |__negative regulation of cardiac muscle cell differentiation(+) 1 rec.
                                                   |   |__negative regulation of cardiac vascular smooth muscle cell differentiation
                                                   |   |__negative regulation of cardioblast differentiation(+) 4 rec.
                                                   |   |__negative regulation of endocardial cushion cell differentiation
                                                   |__negative regulation of cell development 45 rec.
                                                   |   |__negative regulation of ascospore formation
                                                   |   |__negative regulation of cardiac muscle fiber development
                                                   |   |__negative regulation of cell maturation(+) 1 rec.
                                                   |   |__negative regulation of cell morphogenesis(+)
                                                   |   |__negative regulation of cerebellar neuron development
                                                   |   |__negative regulation of chondrocyte development(+)
                                                   |   |__negative regulation of conidium formation
                                                   |   |__negative regulation of endothelial cell development(+)
                                                   |   |__negative regulation of establishment of blood-brain barrier 1 rec.
                                                   |   |__negative regulation of establishment of Sertoli cell barrier
                                                   |   |__negative regulation of eye photoreceptor cell development(+) 3 rec.
                                                   |   |__negative regulation of hemopoiesis(+)
                                                   |   |__negative regulation of Hulle cell development
                                                   |   |__negative regulation of intestinal epithelial cell development
                                                   |   |__negative regulation of male germ-line stem cell asymmetric division
                                                   |   |__negative regulation of metula development
                                                   |   |__negative regulation of neurogenesis(+) 41 rec.
                                                   |   |__negative regulation of oocyte development
                                                   |   |__negative regulation of oogenesis
                                                   |   |__negative regulation of phialide development
                                                   |   |__negative regulation of sarcomere organization
                                                   |   |__negative regulation of skeletal muscle fiber development
                                                   |   |__negative regulation of spore encystment on host(+)
                                                   |   |__negative regulation of type B pancreatic cell development
                                                   |__negative regulation of cell differentiation involved in embryonic placenta development
                                                   |__negative regulation of cell differentiation involved in phenotypic switching
                                                   |   |__negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
                                                   |__negative regulation of cell differentiation involved in stem cell population maintenance
                                                   |__negative regulation of cell fate commitment 21 rec.
                                                   |   |__negative regulation of anterior neural cell fate commitment of the neural plate(+)
                                                   |   |__negative regulation of cell fate determination(+)
                                                   |   |__negative regulation of cell fate specification(+) 15 rec.
                                                   |   |__negative regulation of establishment or maintenance of neuroblast polarity
                                                   |   |__negative regulation of R7 cell fate commitment
                                                   |   |__negative regulation of retinal cone cell fate commitment(+)
                                                   |   |__negative regulation of sevenless signaling pathway 6 rec.
                                                   |   |__negative regulation of T-helper 17 cell lineage commitment
                                                   |   |__negative regulation of venous endothelial cell fate commitment(+)
                                                   |__negative regulation of chondrocyte differentiation
                                                   |   |__negative regulation of chondrocyte development(+)
                                                   |__negative regulation of embryo sac central cell differentiation
                                                   |__negative regulation of embryo sac egg cell differentiation
                                                   |__negative regulation of endodermal cell differentiation
                                                   |   |__negative regulation of endodermal cell fate specification
                                                   |__negative regulation of epithelial cell differentiation
                                                   |   |__inhibition of neuroepithelial cell differentiation(+)
                                                   |   |__negative regulation of cumulus cell differentiation
                                                   |   |__negative regulation of endothelial cell differentiation(+)
                                                   |   |__negative regulation of epidermal cell differentiation(+)
                                                   |   |__negative regulation of epithelial cell differentiation involved in kidney development(+)
                                                   |   |__negative regulation of establishment of Sertoli cell barrier
                                                   |   |__negative regulation of hepatocyte differentiation
                                                   |   |__negative regulation of intestinal epithelial cell development
                                                   |   |__negative regulation of lens fiber cell differentiation
                                                   |   |__negative regulation of lung ciliated cell differentiation
                                                   |   |__negative regulation of lung goblet cell differentiation
                                                   |   |__negative regulation of pancreatic A cell differentiation
                                                   |   |__negative regulation of polarized epithelial cell differentiation
                                                   |__negative regulation of epithelial to mesenchymal transition
                                                   |   |__negative regulation of cardiac epithelial to mesenchymal transition(+)
                                                   |   |__negative regulation of neural crest formation(+)
                                                   |__negative regulation of fat cell differentiation
                                                   |   |__negative regulation of beige fat cell differentiation
                                                   |   |__negative regulation of brown fat cell differentiation
                                                   |   |__negative regulation of white fat cell differentiation
                                                   |__negative regulation of hematopoietic progenitor cell differentiation 1 rec.
                                                   |   |__negative regulation of hematopoietic stem cell differentiation 1 rec.
                                                   |   |__negative regulation of lymphoid progenitor cell differentiation(+)
                                                   |   |__negative regulation of myeloid progenitor cell differentiation
                                                   |__negative regulation of hemocyte differentiation 19 rec.
                                                   |   |__negative regulation of crystal cell differentiation 7 rec.
                                                   |   |__negative regulation of lamellocyte differentiation 9 rec.
                                                   |   |__negative regulation of plasmatocyte differentiation 3 rec.
                                                   |__negative regulation of macrophage derived foam cell differentiation
                                                   |__negative regulation of mesodermal cell differentiation
                                                   |   |__negative regulation of mesodermal cell fate specification(+)
                                                   |__negative regulation of metanephric DCT cell differentiation
                                                   |__negative regulation of muscle cell differentiation 2 rec.
                                                   |   |__negative regulation of smooth muscle cell differentiation(+)
                                                   |   |__negative regulation of striated muscle cell differentiation(+) 1 rec.
                                                   |__negative regulation of myeloid cell differentiation
                                                   |   |__negative regulation of erythrocyte differentiation
                                                   |   |__negative regulation of megakaryocyte differentiation
                                                   |   |__negative regulation of myeloid leukocyte differentiation(+)
                                                   |   |__negative regulation of platelet formation
                                                   |__negative regulation of myoblast differentiation
                                                   |   |__negative regulation of cardiac muscle cell myoblast differentiation
                                                   |__negative regulation of myofibroblast differentiation
                                                   |__negative regulation of neuron differentiation 15 rec.
                                                   |   |__negative regulation of amacrine cell differentiation
                                                   |   |__negative regulation of cerebellar neuron development
                                                   |   |__negative regulation of dopaminergic neuron differentiation(+)
                                                   |   |__negative regulation of forebrain neuron differentiation
                                                   |   |__negative regulation of glutamatergic neuron differentiation
                                                   |   |__negative regulation of mechanoreceptor differentiation(+)
                                                   |   |__negative regulation of photoreceptor cell differentiation(+) 13 rec.
                                                   |   |__negative regulation of spinal cord association neuron differentiation
                                                   |   |__negative regulation of stomach neuroendocrine cell differentiation
                                                   |__negative regulation of osteoblast differentiation
                                                   |__negative regulation of pigment cell differentiation 1 rec.
                                                   |   |__negative regulation of cyanophore differentiation
                                                   |   |__negative regulation of erythrophore differentiation
                                                   |   |__negative regulation of iridophore differentiation
                                                   |   |__negative regulation of leucophore differentiation
                                                   |   |__negative regulation of melanocyte differentiation(+)
                                                   |   |__negative regulation of xanthophore differentiation
                                                   |__negative regulation of plant epidermal cell differentiation
                                                   |   |__negative regulation of atrichoblast fate specification
                                                   |   |__negative regulation of trichoblast fate specification
                                                   |__negative regulation of skeletal muscle cell differentiation
                                                   |   |__negative regulation of satellite cell differentiation
                                                   |   |__negative regulation of skeletal muscle fiber differentiation(+)
                                                   |__negative regulation of sorocarp spore cell differentiation
                                                   |__negative regulation of sorocarp stalk cell differentiation
                                                   |__negative regulation of spermatid nuclear differentiation
                                                   |__negative regulation of stem cell differentiation 11 rec.
                                                   |   |__negative regulation of cardioblast differentiation(+) 4 rec.
                                                   |   |__negative regulation of hematopoietic stem cell differentiation 1 rec.
                                                   |   |__negative regulation of mesenchymal stem cell differentiation(+)
                                                   |   |__negative regulation of neural crest cell differentiation(+)
                                                   |__negative regulation of synergid differentiation
                                                   |__negative regulation of tendon cell differentiation
                                                   |__negative regulation of transdifferentiation
                                                   |__negative regulation of vasculogenesis
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Is a regulation of cell differentiation
negative regulation of cellular process
negative regulation of developmental process
Part of
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Synonyms
  • "down regulation of cell differentiation" EXACT
    "down-regulation of cell differentiation" EXACT
    "downregulation of cell differentiation" EXACT
    "inhibition of cell differentiation" NARROW
Secondary IDs
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