FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term nuclear protein-containing complex ID (Ontology) GO:0140513 (Gene Ontology)
Definition A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.
Also Known As "nuclear complex"
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 nuclear protein-containing complex (all annotations which use CV term, excluding "NOT" statements)       1
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cellular_component
 |__protein-containing complex____________
intracellular membrane-bounded organelle  |
 |__nucleus_______________________________|
                                          nuclear protein-containing complex  1052 rec.
                                           |__5-lipoxygenase complex
                                           |__activated SUMO-E1 ligase complex
                                           |__apolipoprotein B mRNA editing enzyme complex
                                           |__ARC complex
                                           |__ATR-ATRIP complex 1 rec.
                                           |__box H/ACA scaRNP complex
                                           |__box H/ACA snoRNP complex 5 rec.
                                           |__box H/ACA telomerase RNP complex
                                           |__BRCA1-A complex
                                           |__BRCA1-B complex 1 rec.
                                           |__BRCA1-C complex
                                           |__BRCA1-Rad51 complex
                                           |__BRCA2-BRAF35 complex
                                           |__BRISC complex
                                           |__CAK-ERCC2 complex
                                           |__carboxy-terminal domain protein kinase complex 18 rec.
                                           |   |__cyclin/CDK positive transcription elongation factor complex(+) 5 rec.
                                           |   |__transcription factor TFIIH holo complex(+) 13 rec.
                                           |__catenin-TCF7L2 complex
                                           |   |__beta-catenin-TCF7L2 complex
                                           |   |__gamma-catenin-TCF7L2 complex
                                           |__CBF3 complex
                                           |__CENP-A recruiting complex
                                           |__CENP-T-W-S-X complex
                                           |__checkpoint clamp complex 4 rec.
                                           |__CHOP-ATF3 complex
                                           |__chromatin silencing complex 6 rec.
                                           |   |__chromatin lock complex
                                           |   |__eNoSc complex
                                           |   |__HUSH complex
                                           |   |__HUSH2 complex
                                           |   |__RENT complex
                                           |__COMA complex
                                           |__COP9 signalosome 14 rec.
                                           |__Cry-Per complex
                                           |__Ctf18 RFC-like complex 3 rec.
                                           |__CURI complex 2 rec.
                                           |__DASH complex
                                           |__Dbf4-dependent protein kinase complex 4 rec.
                                           |__delta DNA polymerase complex 4 rec.
                                           |__DNA helicase A complex
                                           |__DNA ligase III-XRCC1 complex
                                           |__DNA ligase IV complex 2 rec.
                                           |__DNA polymerase III, clamp loader chi/psi subcomplex
                                           |__DNA polymerase III, clamp loader complex
                                           |   |__DNA polymerase III, clamp loader chi/psi subcomplex
                                           |__DNA polymerase III, core complex
                                           |   |__DNA polymerase III, proofreading complex
                                           |__DNA polymerase III, proofreading complex
                                           |__DNA replication factor A complex 3 rec.
                                           |__DNA replication factor C core complex
                                           |__DNA replication preinitiation complex 14 rec.
                                           |   |__CMG complex 12 rec.
                                           |   |__GINS complex 5 rec.
                                           |__DNA-dependent protein kinase complex
                                           |__DNA-dependent protein kinase-DNA ligase 4 complex 2 rec.
                                           |__dosage compensation complex 8 rec.
                                           |   |__X chromosome located dosage compensation complex, transcription activating 8 rec.
                                           |__DUBm complex 4 rec.
                                           |__E.F.G complex
                                           |__epsilon DNA polymerase complex 5 rec.
                                           |__exon-exon junction complex 7 rec.
                                           |   |__exon-exon junction subcomplex mago-y14
                                           |__FANCM-MHF complex
                                           |__Fanconi anaemia nuclear complex 1 rec.
                                           |__FHL2-CREB complex
                                           |__FHL3-CREB complex
                                           |__GATA1-TAL1-TCF3-Lmo2 complex
                                           |__GATA2-TAL1-TCF3-Lmo2 complex
                                           |__histone deacetylase complex 37 rec.
                                           |   |__HDA1 complex
                                           |   |__NuRD complex(+) 9 rec.
                                           |   |__Rpd3L-Expanded complex 1 rec.
                                           |   |__Set3 complex 1 rec.
                                           |   |__Sin3-type complex(+) 12 rec.
                                           |   |__Snt2C complex
                                           |   |__Swr1 complex 9 rec.
                                           |__histone H3-K14 acetyltransferase complex 1 rec.
                                           |   |__Mst2 histone acetyltransferase complex
                                           |__histone methyltransferase complex 48 rec.
                                           |   |__CLRC complex
                                           |   |__ESC/E(Z) complex 10 rec.
                                           |   |__MLL1/2 complex(+) 11 rec.
                                           |   |__MLL3/4 complex 12 rec.
                                           |   |__nucleosomal methylation activator complex
                                           |   |__Set1C/COMPASS complex 17 rec.
                                           |__histone pre-mRNA 3'end processing complex 4 rec.
                                           |__INTAC complex 16 rec.
                                           |__integrator complex 16 rec.
                                           |__Ku70:Ku80 complex 3 rec.
                                           |__Lid2 complex
                                           |__LinE complex
                                           |__MAML2-RBP-Jkappa-ICN1 complex
                                           |__MAML2-RBP-Jkappa-ICN2 complex
                                           |__MAML2-RBP-Jkappa-ICN3 complex
                                           |__MAML2-RBP-Jkappa-ICN4 complex
                                           |__MAML3-RBP-Jkappa-ICN1 complex
                                           |__MAML3-RBP-Jkappa-ICN2 complex
                                           |__MAML3-RBP-Jkappa-ICN3 complex
                                           |__MAML3-RBP-Jkappa-ICN4 complex
                                           |__mediator complex 35 rec.
                                           |__Mei2 nuclear dot complex
                                           |__meiotic recombination initiation complex
                                           |__microprocessor complex 2 rec.
                                           |__mitotic checkpoint complex 1 rec.
                                           |   |__mitotic checkpoint complex, CDC20-MAD2 subcomplex
                                           |__mitotic checkpoint complex, CDC20-MAD2 subcomplex
                                           |__Mpp10 complex 3 rec.
                                           |__Mre11 complex 4 rec.
                                           |__mRNA capping enzyme complex 1 rec.
                                           |__mRNA cleavage factor complex 18 rec.
                                           |   |__mRNA cleavage and polyadenylation specificity factor complex 10 rec.
                                           |   |__mRNA cleavage stimulating factor complex 3 rec.
                                           |__MTREC complex
                                           |__MutLalpha complex 3 rec.
                                           |__MutLbeta complex
                                           |__MutSalpha complex 3 rec.
                                           |__MutSbeta complex
                                           |__MutSgamma complex
                                           |__Myb complex 12 rec.
                                           |__NF-kappaB complex
                                           |   |__NF-kappaB p50/p65 complex
                                           |__Noc complex 5 rec.
                                           |   |__Noc1p-Noc2p complex 2 rec.
                                           |   |__Noc2p-Noc3p complex 2 rec.
                                           |   |__Noc4p-Nop14p complex 2 rec.
                                           |__nuclear aryl hydrocarbon receptor complex
                                           |__nuclear cyclin-dependent protein kinase holoenzyme complex 24 rec.
                                           |   |__CKM complex 6 rec.
                                           |   |__cyclin/CDK positive transcription elongation factor complex(+) 5 rec.
                                           |   |__transcription factor TFIIH holo complex(+) 13 rec.
                                           |__nuclear DNA replication factor C complex
                                           |   |__DNA replication factor C core complex
                                           |__nuclear DNA-directed RNA polymerase complex 88 rec.
                                           |   |__alpha DNA polymerase:primase complex 5 rec.
                                           |   |__RNA polymerase II, core complex 14 rec.
                                           |   |__RNA polymerase II, holoenzyme(+) 83 rec.
                                           |__nuclear exosome (RNase complex) 11 rec.
                                           |   |__nucleolar exosome (RNase complex)
                                           |__nuclear exosome targeting complex
                                           |__nuclear membrane complex Bqt3-Bqt4
                                           |__nuclear membrane protein complex 5 rec.
                                           |   |__nuclear membrane microtubule tethering complex(+) 3 rec.
                                           |__nuclear origin of replication recognition complex 7 rec.
                                           |__nuclear pore 51 rec.
                                           |   |__cytoplasmic side of nuclear pore
                                           |   |__nuclear pore central transport channel 8 rec.
                                           |   |__nuclear pore cytoplasmic filaments 4 rec.
                                           |   |__nuclear pore inner ring 4 rec.
                                           |   |__nuclear pore linkers
                                           |   |__nuclear pore nuclear basket 4 rec.
                                           |   |__nuclear pore outer ring 8 rec.
                                           |   |__nuclear pore transmembrane ring 2 rec.
                                           |   |__nucleoplasmic side of nuclear pore
                                           |__nuclear pore central transport channel 8 rec.
                                           |__nuclear pore cytoplasmic filaments 4 rec.
                                           |__nuclear pore inner ring 4 rec.
                                           |__nuclear pore linkers
                                           |__nuclear pore nuclear basket 4 rec.
                                           |__nuclear pore outer ring 8 rec.
                                           |__nuclear pore transmembrane ring 2 rec.
                                           |__nuclear pre-replicative complex 2 rec.
                                           |__nuclear proteasome complex
                                           |   |__nuclear proteasome core complex
                                           |   |__nuclear proteasome regulatory particle
                                           |__nuclear proteasome core complex
                                           |   |__nuclear proteasome core complex, alpha-subunit complex
                                           |   |__nuclear proteasome core complex, beta-subunit complex
                                           |__nuclear proteasome core complex, alpha-subunit complex
                                           |__nuclear proteasome core complex, beta-subunit complex
                                           |__nuclear proteasome regulatory particle
                                           |   |__nuclear proteasome regulatory particle, base subcomplex
                                           |   |__nuclear proteasome regulatory particle, lid subcomplex
                                           |__nuclear proteasome regulatory particle, base subcomplex
                                           |__nuclear proteasome regulatory particle, lid subcomplex
                                           |__nuclear replisome 12 rec.
                                           |   |__alpha DNA polymerase:primase complex 5 rec.
                                           |   |__delta DNA polymerase complex 4 rec.
                                           |   |__DNA replication factor A complex 3 rec.
                                           |   |__nuclear DNA replication factor C complex
                                           |__nuclear RNA export factor complex 1 rec.
                                           |__nuclear RNA-directed RNA polymerase complex 1 rec.
                                           |__nuclear telomere cap complex
                                           |   |__CST complex
                                           |   |__shelterin complex
                                           |__nuclear ubiquitin ligase complex 32 rec.
                                           |   |__anaphase-promoting complex 19 rec.
                                           |   |__Asi complex
                                           |   |__BCOR complex
                                           |   |__BRCA1-BARD1 complex
                                           |   |__CLRC complex
                                           |   |__nuclear SCF ubiquitin ligase complex
                                           |   |__PRC1 complex 12 rec.
                                           |   |__SUMO-targeted ubiquitin ligase complex 1 rec.
                                           |__nucleolar ribonuclease P complex 7 rec.
                                           |__nucleosome disassembly/reassembly complex
                                           |__nucleotide-excision repair complex 5 rec.
                                           |   |__Ddb1-Ckn1 complex
                                           |   |__Ddb1-Wdr21 complex
                                           |   |__ERCC4-ERCC1 complex 1 rec.
                                           |   |__nucleotide-excision repair factor 1 complex 3 rec.
                                           |   |__nucleotide-excision repair factor 2 complex 1 rec.
                                           |   |__nucleotide-excision repair factor 3 complex(+) 1 rec.
                                           |   |__nucleotide-excision repair factor 4 complex
                                           |   |__RAD52-ERCC4-ERCC1 complex
                                           |   |__XPC complex 1 rec.
                                           |__P-TEFb-cap methyltransferase complex
                                           |__PcG protein complex 36 rec.
                                           |   |__ESC/E(Z) complex 10 rec.
                                           |   |__PR-DUB complex 3 rec.
                                           |   |__PRC1 complex 12 rec.
                                           |__PCNA complex 2 rec.
                                           |__PCNA-p21 complex
                                           |__PDX1-PBX1b-MRG1 complex
                                           |__PeBoW complex 3 rec.
                                           |__Pwp2p-containing subcomplex of 90S preribosome 5 rec.
                                           |__Rad51B-Rad51C complex
                                           |__Rad51B-Rad51C-Rad51D-XRCC2 complex 2 rec.
                                           |__Rad51C-XRCC3 complex 1 rec.
                                           |__RC-1 DNA recombination complex
                                           |__RCAF complex 48 rec.
                                           |__replication fork protection complex 3 rec.
                                           |__RES complex
                                           |__RGS6-DNMT1-DMAP1 complex
                                           |__Rhino-Deadlock-Cutoff Complex 1 rec.
                                           |__RITS complex
                                           |__RNA polymerase I complex 14 rec.
                                           |__RNA polymerase I transcription regulator complex 3 rec.
                                           |   |__RNA polymerase I core factor complex 1 rec.
                                           |   |__RNA polymerase I upstream activating factor complex
                                           |   |__RNA polymerase transcription factor SL1 complex 3 rec.
                                           |__RNA polymerase I transcription repressor complex
                                           |__RNA polymerase II termination complex
                                           |__RNA polymerase II transcription regulator complex 139 rec.
                                           |   |__activin responsive factor complex
                                           |   |__ATF1-ATF4 transcription factor complex
                                           |   |__ATF4-CREB1 transcription factor complex
                                           |   |__beta-catenin-TCF complex(+) 5 rec.
                                           |   |__C/EBP complex
                                           |   |__CCAAT-binding factor complex 4 rec.
                                           |   |__CHOP-ATF4 complex
                                           |   |__CHOP-C/EBP complex
                                           |   |__CLOCK-BMAL transcription complex 1 rec.
                                           |   |__core mediator complex 12 rec.
                                           |   |__core-binding factor complex 2 rec.
                                           |   |__CSL-Notch-Mastermind transcription factor complex 4 rec.
                                           |   |__ecdysone receptor holocomplex(+) 3 rec.
                                           |   |__heteromeric SMAD protein complex 4 rec.
                                           |   |__insulin control element activator complex
                                           |   |__ISGF3 complex
                                           |   |__M/G1 phase-specific MADS box-forkhead transcription factor complex
                                           |   |__MBF transcription complex
                                           |   |__Myc-Max complex
                                           |   |__Nkx-2.5 complex
                                           |   |__Pi Mi complex
                                           |   |__Pip2-Oaf1 complex
                                           |   |__Rb-E2F complex 5 rec.
                                           |   |__SBF transcription complex
                                           |   |__SMN-Gemin2 complex 2 rec.
                                           |   |__SRF-myogenin-E12 complex
                                           |   |__TEAD-YAP complex
                                           |   |__transcription factor AP-1 complex(+) 2 rec.
                                           |   |__transcription factor TFIIA complex 7 rec.
                                           |   |__transcription factor TFIID complex(+) 29 rec.
                                           |   |__transcription factor TFIIE complex 3 rec.
                                           |   |__transcription factor TFIIF complex 3 rec.
                                           |   |__transcription factor TFIIH core complex(+) 7 rec.
                                           |   |__transcription factor TFIIH holo complex(+) 13 rec.
                                           |   |__transcription factor TFIIK complex 2 rec.
                                           |   |__transcription factor TFTC complex
                                           |   |__upstream stimulatory factor complex
                                           |__RNA polymerase II transcription repressor complex 22 rec.
                                           |   |__beta-catenin-ICAT complex
                                           |   |__Cyc8(Ssn6)-Tup1 general repressor complex
                                           |   |__DRM complex 11 rec.
                                           |   |__Mad-Max complex
                                           |   |__Mad-Max-mSin3A complex
                                           |   |__Mad-Max-mSin3B complex
                                           |   |__negative cofactor 2 complex 2 rec.
                                           |   |__Tle3-Aes complex
                                           |__RNA polymerase III complex 18 rec.
                                           |__RNA polymerase III transcription repressor complex
                                           |__RNA polymerase IV complex
                                           |__RNA polymerase IV transcription repressor complex
                                           |__RNA polymerase V complex
                                           |__RNA polymerase V transcription repressor complex
                                           |__Slx1-Slx4 complex 2 rec.
                                           |__small nuclear ribonucleoprotein complex 109 rec.
                                           |   |__7SK snRNP 4 rec.
                                           |   |__spliceosomal snRNP complex(+) 91 rec.
                                           |   |__U7 snRNP 3 rec.
                                           |__small-subunit processome 46 rec.
                                           |__SMC loading complex 2 rec.
                                           |   |__Scc2-Scc4 cohesin loading complex 1 rec.
                                           |   |__Wpl/Pds5 cohesin loading/unloading complex
                                           |__Smp focus
                                           |__SOSS complex 2 rec.
                                           |__spliceosomal complex 200 rec.
                                           |   |__catalytic step 1 spliceosome(+) 3 rec.
                                           |   |__catalytic step 2 spliceosome(+) 126 rec.
                                           |   |__post-mRNA release spliceosomal complex(+) 10 rec.
                                           |   |__post-spliceosomal complex(+) 3 rec.
                                           |   |__precatalytic spliceosome(+) 142 rec.
                                           |   |__prespliceosome(+) 15 rec.
                                           |   |__supraspliceosomal complex
                                           |   |__trans spliceosomal complex
                                           |   |__U2-type spliceosomal complex(+) 38 rec.
                                           |   |__U12-type spliceosomal complex(+) 14 rec.
                                           |__SUMO activating enzyme complex 2 rec.
                                           |__survivin complex
                                           |__SWI/SNF superfamily-type complex 68 rec.
                                           |   |__B-WICH complex
                                           |   |__bBAF complex
                                           |   |__brahma complex 20 rec.
                                           |   |__CHD-type complex(+) 9 rec.
                                           |   |__esBAF complex
                                           |   |__GBAF complex
                                           |   |__INO80-type complex(+) 21 rec.
                                           |   |__ISWI-type complex(+) 19 rec.
                                           |   |__mBAF complex
                                           |   |__nBAF complex 2 rec.
                                           |   |__npBAF complex 1 rec.
                                           |   |__RSC-type complex 2 rec.
                                           |   |__SWI/SNF complex 7 rec.
                                           |__Swi5-Sfr1 complex
                                           |__Swi5-Swi2 complex
                                           |__synapsis initiation complex
                                           |__t-UTP complex 3 rec.
                                           |__telomerase holoenzyme complex 2 rec.
                                           |   |__box H/ACA telomerase RNP complex
                                           |   |__telomerase catalytic core complex
                                           |__THO complex 7 rec.
                                           |   |__nucleoplasmic THO complex 1 rec.
                                           |   |__THO complex part of transcription export complex 6 rec.
                                           |__Tor2-Mei2-Ste11 complex
                                           |__TRAMP complex 4 rec.
                                           |__transcription elongation factor complex 51 rec.
                                           |   |__Cdc73/Paf1 complex 14 rec.
                                           |   |__cyclin/CDK positive transcription elongation factor complex(+) 5 rec.
                                           |   |__DSIF complex 3 rec.
                                           |   |__elongin complex 5 rec.
                                           |   |__FACT complex 3 rec.
                                           |   |__NELF complex 5 rec.
                                           |   |__nucleoplasmic THO complex 1 rec.
                                           |   |__super elongation complex 9 rec.
                                           |__transcription export complex 10 rec.
                                           |   |__THO complex part of transcription export complex 6 rec.
                                           |__transcription export complex 2 4 rec.
                                           |__tRNA-intron endonuclease complex 4 rec.
                                           |__U2AF complex 5 rec.
                                           |__UTP-C complex 2 rec.
                                           |__XRCC2-RAD51D complex
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Is a protein-containing complex
Part of nucleus
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Synonyms
  • "nuclear complex" EXACT
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