FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term opioid growth factor receptor signaling pathway ID (Ontology) GO:0140626 (Gene Ontology)
Definition The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A).[ PubMed:19675283 PubMed:19923357 ]
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cell communication______________
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                                signal transduction
                                 |__opioid growth factor receptor signaling pathway
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Wikipedia:OGFr
Wikipedia:Opioid_receptor