FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term GDF15-GFRAL signaling pathway ID (Ontology) GO:0160144 (Gene Ontology)
Definition The series of molecular signals initiated by GDF15 binding to GFRAL coreceptor, triggering RET autophosphorylation and activation, in response to stress.[ PubMed:30639358 PubMed:31535977 PubMed:33593916 PubMed:37437602 ]
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response to stress
 |__cellular response to stress________________________________________
cell surface receptor protein tyrosine kinase signaling pathway        |
 |__glial cell-derived neurotrophic factor receptor signaling pathway__|
cellular response to stimulus                                          |
 |__cellular response to stress________________________________________|
                                                                       GDF15-GFRAL signaling pathway
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Is a cellular response to stress
glial cell-derived neurotrophic factor receptor signaling pathway
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