FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term polyuridylation-dependent mRNA catabolic process ID (Ontology) GO:1990074 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.[ PubMed:23503588 ]
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RNA catabolic process
 |__mRNA catabolic process__________________________________
macromolecule catabolic process                             |
 |__modification-dependent macromolecule catabolic process__|
negative regulation of gene expression                      |
 |__mRNA catabolic process__________________________________|
 |__mRNA destabilization____________________________________|
mRNA metabolic process                                      |
 |__mRNA catabolic process__________________________________|
regulation of mRNA stability                                |
 |__mRNA destabilization____________________________________|
RNA destabilization                                         |
 |__mRNA destabilization____________________________________|
positive regulation of mRNA catabolic process               |
 |__mRNA destabilization____________________________________|
                                                            polyuridylation-dependent mRNA catabolic process
                                                             |__polyuridylation-dependent decapping of nuclear-transcribed mRNA
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Is a mRNA catabolic process
modification-dependent macromolecule catabolic process
mRNA destabilization
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