FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3R)E40
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General Information
Symbol
Df(3R)E40
Species
D. melanogaster
Name
FlyBase ID
FBab0002563
Feature type
chromosomal_deletion
Computed Breakpoints include

100C5;100F1-100F5

Features within 100C5--100F5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
PM hybrid dysgenesis
(Locke et al., 1988)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wisotzkey et al., 1998, Harbecke and Lengyel, 1995, Locke et al., 1988)
Breakpoints

100C5-100D1;100F1-100F5

(Locke et al., 1988)

100C5-100D1;100F

(Harbecke and Lengyel, 1995)

100C5;100F1-100F5

(Wisotzkey et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

rod << bk1 << Med << bk2

Genetic mapping information
Comments
Comments on Cytology

Right breakpoint is at the tip of 3R.

(Locke et al., 1988)

Left limit of break 1 from polytene analysis (FBrf0048198) Right limit of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (FBrf0048198)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Med
(Das et al., 1998, Hudson et al., 1998, Wisotzkey et al., 1998, Raftery, 1995.4.6, Raftery et al., 1995)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
rod
(Wisotzkey et al., 1998)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Effect on variegation of y in In(1)y3P and Sb in T(2;3)SbV studied: inactivation of y occurs independently of inactivation of Sb.

    (Bishop, 1992)

    Dominantly enhances position effect variegation at the w locus caused by In(1)wm4, C(1;YL)wmMc or T(1;4)wm5 and position effect variegation at the y locus caused by In(1)y3P. Position effect variegation at the w locus is not seen when Df(3R)E40 is combined with In(1)wm4rv5, In(1)wm4rv6 or In(1)wm4rv26.

    (Locke et al., 1988)
    NOT in combination with other aberrations

    Deficient embryos show a variably penetrant mutant midgut phenotype: central constriction absent.

    (Bilder and Scott, 1995)

    Homozygous embryos do not complete head involution or dorsal closure, and tracheae are not connected. Midgut constrictions are incomplete, Malpighian tubules have a variable diameter along their length and the hindgut is sometimes shorter than normal.

    (Harbecke and Lengyel, 1995)

    Strictly maternal enhancer of dpphr4 lethality. The lethal interaction is due to a loss of dorsal-most fates in the embryos, demonstrated by loss of amnioserosa cells.

    (Raftery et al., 1995)

    Homozygous lethal.

    (Locke et al., 1988)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(3R)E40
    (Popkova et al., 2012, Takaesu et al., 2005)
    E40
    (Locke et al., 1988)
    Name Synonyms
    Secondary FlyBase IDs
      References (14)