FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)Pmi-PGRP-LD
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General Information
Symbol
Df(3L)Pmi-PGRP-LD
Species
D. melanogaster
Name
FlyBase ID
FBab0047094
Feature type
chromosomal_deletion
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
ends-out gene targeting
(Rival et al., 2011)
FLPase
(Rival et al., 2011)
I-SceI
(Rival et al., 2011)
Class of aberration (relative to wild type)
chromosomal_deletion
(Rival et al., 2011, Rival et al., 2011)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Rival et al., 2011, Rival et al., 2011)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Ends-out targeting has resulted in a deletion that covers a genomic region starting from 140bp upstream of the Pmi ATG codon to 77bp downstream of the PGRP-LD stop codon. The deleted sequence is replaced by a w marker.

(Rival et al., 2011)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
PGRP-LD
(Rival et al., 2011)
Pmi
(Rival et al., 2011)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutant flies are neurologically impaired from eclosion.

    The size of the mitochondria is increased while the number of mitochondria is reduced in a number of mutant larval and adult tissues (adult flight muscles, adult proventriculus, ovaries, larval fat body and larval salivary gland) compared to wild type. In the mutant adult flight muscles, the enlarged mitochondria are round in shape but contain intact internal structures.

    (Rival et al., 2011)

    Mutants hatch as morphologically normal adults but they display paralysis under stress conditions ("bang sensitivity"). The mitochondria are larger than normal and round in shape, but they have a normal ultrastructure.

    (Rival et al., 2011)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(3L)Pmi-PGRP-LD
    PMI_PGRP-LD mutant
    (Rival et al., 2011)
    PMI_PGRP-LD-mutant
    (Rival et al., 2011)
    Name Synonyms
    Secondary FlyBase IDs
      References (2)