FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\qua11
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General Information
Symbol
Dmel\qua11
Species
D. melanogaster
Name
FlyBase ID
FBal0014164
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
quaQE24
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Egg chambers appear normal until early stage 10, but after stage 10 the nurse cells fail to regress and deliver their contents into the oocyte. Consequently the oocytes are approximately half the normal size. The cytoplasmic actin bundles that assemble in wild type nurse cells just prior to the onset of rapid transport are missing. The nurse cell nuclei assume an elongated morphology and often extend through the ring canals. The few eggs laid by these females fail to develop.

Eggs are tiny due to a failure to transport nurse cell content into the oocyte.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Schupbach and Wieschaus.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)