FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\qui2
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General Information
Symbol
Dmel\qui2
Species
D. melanogaster
Name
FlyBase ID
FBal0028522
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
quiPX61
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Females exhibit reduced quantities of yolk in the oocytes due to defects in the uptake mechanism of vitellogenin: partial failure of endocytotic vitellogenin uptake from the haemolymph. Wild type ovaries transplanted into mutant females develop normally but mutant ovaries transplanted into wild type females do not develop normally. Results demonstrate the ability to take up vitellogenin from the haemolymph is attributable to developmental defects within the ovary.

Ovaries contain egg chambers with variable numbers of pseudo-nurse cells. Pseudo-nurse cells nuclei are polyploid.

Abnormalities in follicle cell migration: open ended chorion.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)