FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

loss of function allele

ID (Ontology)

FBcv:0000287 (FlyBase CV)

Definition

An allele that either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.[ FlyBase:FBrf0049147 ]

Comment

Links to External Ontologies

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Alleles (FBal)	ALLELE_CLASS
Alleles (FBal)	PROMOTED_CLASS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Alleles
loss of function allele (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

  allele descriptor
   |__allele class
       |__loss of function allele  10418 rec.
           |__amorphic allele 4323 rec.
           |   |__amorphic allele - genetic evidence(+) 2019 rec.
           |   |__amorphic allele - molecular evidence(+) 2399 rec.
           |   |__temperature conditional amorphic allele(+) 8 rec.
           |__hypomorphic allele 2958 rec.
           |   |__hypomorphic allele - genetic evidence(+) 2370 rec.
           |   |__hypomorphic allele - molecular evidence(+) 611 rec.
           |   |__temperature conditional hypomorphic allele(+) 62 rec.
           |__temperature conditional loss of function allele 122 rec.
               |__cold sensitive loss of function allele(+) 11 rec.
               |__heat sensitive loss of function allele(+) 100 rec.
               |__temperature conditional amorphic allele(+) 8 rec.
               |__temperature conditional hypomorphic allele(+) 62 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	allele class
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts