FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\blotM55
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General Information
Symbol
Dmel\blotM55
Species
D. melanogaster
Name
FlyBase ID
FBal0100386
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

A small genomic deletion in ther vicinity of the P{lArB} has occurred, leaving part of the P{lArB} in the genome.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Lethality acts in the second larval instar. Phenotype similar to blot01658. Females with germ line clones show strongly reduced fertility. Affected embryos first show a defect as a delay in the formation of pole cells and a frequent reduction in number of pole cells. As nuclei reach the periphery, few actin filaments are present and no organisation into F-actin caps or mitotic pseudo-cleavage furrows can be detected. The spacing between nuclei becomes irregular. Many nuclei have abnormal shape, fuse and drop into the interior of the embryo. Cellularisation completely fails. The embryo remains a polynucleate mass, which gradually deteriorates.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
blotM55
Name Synonyms
Secondary FlyBase IDs
    References (1)