FlyBase Allele Report: Dmel\fng[a.UAS]

General Information

Symbol

Dmel\fng^a.UAS

Species

D. melanogaster

Name

antisense Saccharomyces cerevisiae UAS construct

FlyBase ID

FBal0121774

Feature type

allele

Associated gene

Dmel\fng

Associated Insertion(s)

Carried in Construct

P{UAS-fng.a}

Key Links

Transgenic product class

antisense

(Zhao et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

antisense

(Zhao et al., 2000)

Mutagen

in vitro construct

(Zhao et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-fng.a}

Cytology

Description

UAS regulatory sequences drive expression of fng in the antisense orientation.

(Zhao et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

fng

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

egg chamber, with Scer\GAL4^fng-c606

(Zhao et al., 2000)

follicle cell, with Scer\GAL4^fng-c606

(Zhao et al., 2000)

Detailed Description

Statement

Reference

Many oocytes develop normally in ovaries expressing fng^a.Scer\UAS under the control of Scer\GAL4^fng-c606, although in some egg chambers, there is a failure, at stage 9, of the follicle cells surrounding the nurse cells to migrate normally to the posterior to produce the columnar follicle cells around the oocyte. This ultimately leads to the degeneration of these egg chambers. Similar results are obtained when fng^a.Scer\UAS is expressed under the control of Scer\GAL4^c709.

(Zhao et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

fng^a.Scer\UAS

fng^a.UAS

Name Synonyms

antisense Saccharomyces cerevisiae UAS construct

(Zhao et al., 2000)

Secondary FlyBase IDs

References (1)

Report Sections

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