FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(3)Me101
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General Information
Symbol
Dmel\l(3)Me101
Species
D. melanogaster
Name
FlyBase ID
FBal0159064
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones result in an increase in the density of chaetae in the wing, notum and abdomen, associated with an increase in trichome density and smaller adult cells in the wing. The average size of adult wing cells in homozygous clones is 25.4% smaller than surrounding wild-type cells. Any intervein sector with a mutant clone shows an average reduction in area of 21.9% compared to controls, although the reduction can reach 27.4% when the clone occupies more than 50% of the mosaic sector. The average reduction in cell number for a sector carrying a mutant clone is 14.9% compared to the same wild-type sector. In addition to the size reduction of the intervein sector containing a mutant clone (autonomous effect), there is a corresponding reduction in all other sectors of the same wing (non-autonomous effect), the average reduction in sector size being 8.9% compared to controls. This reduction affects all non-mutant compartments and sectors of the mosaic wing equally, in both the anterior-posterior and proximal-distal axes, irrespective of the position of the mutant clone and whether or not the clone is adjacent to compartment boundaries. Homozygous clones in the notum show an increase in density of both the macro- and microchaetae compared to controls. In the acrostical region, there is a 34.5% increase in density of microchaetae in the mutant territory, which is due both to a reduction in the number of cells between chaetae (3.79 in mutant tissue compared to 5.34 in wild type) and to smaller cells. Heminota containing large clones are smaller than controls (containing fewer cells), but contain higher numbers of microchaetae than controls.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)