FB2026_02 , released June 18, 2026
Allele: Dmel\ShUAS.cJa
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General Information
Symbol
Dmel\ShUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Joiner
FlyBase ID
FBal0316420
Feature type
allele
Associated gene
Dmel\Sh
Associated Insertion(s)
Carried in Construct
P{UAS-Sh.J}
Key Links
Transgenic product class
wild_type
(Ping et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ping et al., 2015)
Mutagen
in vitro construct
(Ping et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Sh.J}
Cytology
Description

UAS regulatory sequences drive expression of Sh.

(Ping et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Sh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of ShScer\UAS.cJa does not suppress the learning defects seen in larvae expressing Hsap\APPAβ1-42.Scer\UAS.cIa pan-neuronally under the control of Scer\GAL4elav.PU.

      Expression of ShScer\UAS.cJa does suppress the progressive climbing defects seen in adult flies expressing Hsap\APPAβ1-42.Scer\UAS.cIa pan-neuronally under the control of Scer\GAL4elav.PU.

      Expression of ShScer\UAS.cJa suppresses the mushroom body neuron cell loss seen in adult flies expressing Hsap\APPAβ1-42.Scer\UAS.cIa pan-neuronally under the control of Scer\GAL4elav.PU at 25 days, but not at 40 days.

      Expression of ShScer\UAS.cJa does not suppress the reduction in lifespan seen when Hsap\APPAβ1-42.Scer\UAS.cIa is expressed under the control of Scer\GAL4elav.PU.

      (Ping et al., 2015)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ShScer\UAS.cJa
      ShUAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Joiner
      Secondary FlyBase IDs
        References (1)