FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-977KO
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General Information
Symbol
Dmel\mir-977KO
Species
D. melanogaster
Name
FlyBase ID
FBal0340203
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
mir-977 KO
Key Links
Genomic Maps

Mutagen
Nature of the Allele
Progenitor genotype
Cytology
Description

21bp deletion in mir-977.

Deletion within the mir-977 locus; no mature miRNA product is produced.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

mir-977KO increases the viability of males, but not of females, as compared to controls. mir-977KO hemizygous males crossed to control females produce significantly more progeny than control males, which is due to the stimulation of ovulation (i.e. a significantly increased egg production per mating) rather than increased embryo viability (i.e. number of eggs hatching is unaffected). Furthermore, mir-977KO does not affect in the mating ability of mutant males with naive females, but results in a slightly higher reduction of female receptivity to re-mating, as compared to control males. The progeny of mir-977KO males present a similar sex ratio as control progeny.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
mir-977KO
Name Synonyms
Secondary FlyBase IDs
    References (2)