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General Information
Name
Sevenless Signaling Pathway Core Components
Species
D. melanogaster
Symbol
SEVL-C
FlyBase ID
FBgg0000935
Date last reviewed
2020-01-16
Number of members
18
Description
Description

The specification of the R7 photoreceptor cell in each ommatidium of the developing Drosophila eye is dependent on activation of Sevenless receptor tyrosine kinase, which acts via the canonical Ras/Raf/MAP kinase cascade to promote the expression of lz and pros. sev, expressed in presumptive R7 cells, is activated by binding to Bride of Sevenless (boss), a seven-transmembrane protein expressed in R8 cells. (Adapted from FBrf0127283 and FBrf0221727).

Notes and selected reviews
Biological Process Gene Ontology (GO) term(s)
Related Gene Groups
Physical Interaction Network
Members (18)
For all members:
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SEVL-C
Sevenless Signaling Pathway Core Components
Secondary FlyBase ID(s)
References (48)