FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
how
FlyBase ID
FBig0000103638
Interaction Network
Interactions Browser links
how network
Reported Interactions
FBrf0217996-1.coIP.WB
Reference
Nir et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
how 

HOW

bait

GFP tag

how 

HOW

prey

HA tag

how 
how 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
how 
dimerization site
mutation disrupting interaction
aa 106

E106G

how 
MAPK-ERK phosphorylation sites
mutation decreasing interaction
aa 59-64

T59A and T64A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Nir et al., 2012)

Dimerization defective how proteins also show reduced levels of phosphorylation in S2R+ cells.

(Nir et al., 2012)
External Crossreferences and Linkouts ( 0 )
References (1)