FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
vls, osk
FlyBase ID
FBig0000108000
Interaction Network
Interactions Browser links
vls network
osk network
Reported Interactions
FBrf0212588-1.PD.WB
Reference
Anne, 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
vls 

Vls

bait

GST tag

vls 
vls 
vls 
vls 
osk 

Osk

prey

S tag

osk 
osk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
vls 
WD repeat 1
sufficient binding region
aa 90-139

coordinates relative to vls-PA

vls 
WD repeat 3
sufficient binding region
aa 187-236

coordinates relative to vls-PA

vls 
WD repeat 4
sufficient binding region
aa 231-286

coordinates relative to vls-PA

vls 
C-terminal region
sufficient binding region
aa 309-367

coordinates relative to vls-PA

osk 
Vls-binding region 1
necessary binding region
aa 260-289

coordinates relative to osk-PA

osk 
Vls-binding region 2
necessary binding region
aa 477-543

coordinates relative to osk-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced by in vitro translation.

(Anne, 2010)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)