FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Reference Report
Open Close
Reference
Citation
Tomari, Y., Zamore, P.D. (2005). MicroRNA Biogenesis: Drosha Can't Cut It without a Partner.  Curr. Biol. 15(2): R61--R64.
FlyBase ID
FBrf0188534
Publication Type
Note
Abstract
The ribonuclease Drosha requires a dedicated double-stranded RNA binding protein to convert long, nuclear primary microRNA transcripts into shorter pre-microRNA stem-loops, the cytoplasmic precursors from which mature microRNAs are ultimately excised.
PubMed ID
15668159
PubMed Central ID
DOI
10.1016/j.cub.2004.12.057
Related Publication(s)
Research paper

Processing of primary microRNAs by the Microprocessor complex.
Denli et al., 2004, Nature 432(7014): 231--235 [FBrf0180557]

The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis.
Landthaler et al., 2004, Curr. Biol. 14(23): 2162--2167 [FBrf0183815]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference
    Genes (5)