Herrera, S.C., Bach, E.A. (2018). Super-Competitors Game the Fitness Sensing System.  Dev. Cell 46(6): 672--674.

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Note

Competitive interactions between neighboring cells require fitness comparison and local killing, but the signals regulating these processes are unknown. In this issue, Alpar et al. (2018) demonstrate that fitter cells secrete serine proteases to create a local burst of active Spätzle, triggering Toll signaling and apoptosis in less fit neighbors.