FB2026_03 , released September 17, 2026
Recombinant Construct: P{UASp-cact.DN.B-LID}
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General Information
Symbol
P{UASp-cact.DN.B-LID}
FlyBase ID
FBtp0148187
Feature type
transgenic_transposable_element
Component Allele(s)
cactDN.UASp.Tag:degron(B-LID)
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele cactDN.UASp.Tag:degron(B-LID)
Transgenic product class
dominant_negative_variant
(Stevens et al., 2021)
missense_variant
(Stevens et al., 2021)
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
cact
Tagged with
Tag:degron(B-LID)
Description

UASp regulatory sequences drive expression of a dominant-negative form of cact in which Ser residues 74, 78 and 116 have been mutated to Ala, rendering the protein insensitive to Tl receptor dependent phosphorylation, and subsequent ubiquitination and degradation. The cact sequence is tagged at the C-terminal end with a light-inducible degron sequence (Tag:degron(B-LID)).

(Stevens et al., 2021)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UASp-cact.DN.B-LID}
(FlyBase, 1992-)
UASp-CactDN-B-LID
(Stevens et al., 2021)
Secondary FlyBase IDs
    References (3)