FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term fumarate hydratase activity ID (Ontology) GO:0004333 (Gene Ontology)
Definition Catalysis of the reaction: (S)-malate = fumarate + H2O.[ EC:4 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 fumarate hydratase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | fumarate hydratase activity       --
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  carbon-oxygen lyase activity
   |__hydro-lyase activity
       |__fumarate hydratase activity  5 rec.
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Is a hydro-lyase activity
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Synonyms
  • "(S)-malate hydro-lyase (fumarate-forming)" RELATED[ EC:4 ]
    "(S)-malate hydro-lyase activity" RELATED[ EC:4 ]
    "fumarase activity" RELATED[ EC:4 ]
    "L-malate hydro-lyase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.2.1.2
KEGG_REACTION:R01082
MetaCyc:FUMHYDR-RXN
Reactome:R-HSA-70982 "FH tetramer hydrates fumarate to L-malate"
RHEA:12460