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General Information
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| Term |
Rab geranylgeranyltransferase activity |
ID (Ontology) |
GO:0004663 (Gene Ontology) |
| Definition |
Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.[ EC:2 PubMed:8621375 ] |
| Also Known As |
"geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" ; "GGTase-II activity" ; "GGTaseII activity" (for all, see Synonyms field below) |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_MOLECULAR_FUNCTION | 3 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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Rab geranylgeranyltransferase activity (all annotations which use CV term, excluding "NOT" statements) | 3 | contributes_to | Rab geranylgeranyltransferase activity | 3 | enables | Rab geranylgeranyltransferase activity | 1 |
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Relationships
