FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term antiporter activity ID (Ontology) GO:0015297 (Gene Ontology)
Definition Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).[ ISBN:0815340729 PubMed:10839820 ]
Also Known As "countertransporter activity" ; "exchange transporter activity" ; "solute:solute antiporter activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
Genes (FBgn)  GO_MOLECULAR_FUNCTION      16
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 antiporter activity (all annotations which use CV term, excluding "NOT" statements)       1     16
     enables | antiporter activity       --      16
Spanning Tree (Parents/Children)
Only view relationship: 
  active transmembrane transporter activity
   |__secondary active transmembrane transporter activity
       |__antiporter activity  49 rec.
           |__(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
           |__acetyl-CoA:CoA antiporter activity
           |__acetylcholine:proton antiporter activity
           |__acridine:proton antiporter activity
           |__agmatine:putrescine antiporter activity
           |__amino acid:monoatomic cation antiporter activity 3 rec.
           |   |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
           |   |__gamma-aminobutyric acid:proton antiporter activity 2 rec.
           |   |__glycine:proton antiporter activity
           |   |__L-alanine:proton antiporter activity
           |   |__L-asparagine, sodium:proton antiporter activity
           |   |__L-glutamate:proton antiporter activity(+) 1 rec.
           |   |__L-glutamine, sodium:proton antiporter activity
           |   |__L-histidine, sodium:proton antiporter activity
           |__arginine:agmatine antiporter activity
           |__arginine:ornithine antiporter activity
           |__aspartate:alanine antiporter activity
           |__ATP:ADP antiporter activity 2 rec.
           |__azole:proton antiporter activity
           |   |__aminotriazole:proton antiporter activity
           |   |__fluconazole:proton antiporter activity
           |   |__L-histidine, sodium:proton antiporter activity
           |__benomyl:proton antiporter activity
           |__bicarbonate:monoatomic anion antiporter activity
           |   |__chloride:bicarbonate antiporter activity(+)
           |__broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
           |__carnitine:O-acyl-L-carnitine antiporter activity
           |__citrate:2-oxoglutarate antiporter activity
           |__citrate:succinate antiporter activity
           |__cycloheximide:proton antiporter activity
           |__cystine:glutamate antiporter activity
           |__folate:monoatomic anion antiporter activity
           |__glutamate:gamma-aminobutyric acid antiporter activity
           |__GTP:GDP antiporter activity
           |__L-aspartate:fumarate antiporter activity
           |__L-histidine:histamine antiporter activity
           |__L-lysine:L-arginine antiporter activity
           |__lysine:cadaverine antiporter activity
           |__metal cation:monoatomic cation antiporter activity 23 rec.
           |   |__calcium:monoatomic cation antiporter activity(+) 15 rec.
           |   |__magnesium:sodium antiporter activity
           |   |__metal cation:proton antiporter activity(+) 10 rec.
           |   |__sodium,bicarbonate:chloride antiporter activity
           |   |__solute:potassium antiporter activity(+) 12 rec.
           |__monoamine:proton antiporter activity
           |__orotate:monoatomic anion antiporter activity
           |__oxoglutarate:malate antiporter activity
           |__polyamine:proton antiporter activity
           |__polyspecific organic cation:proton antiporter activity
           |__putrescine:ornithine antiporter activity
           |__S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity
           |__solute:inorganic anion antiporter activity 9 rec.
           |   |__chloride:bicarbonate antiporter activity(+)
           |   |__chloride:proton antiporter activity 3 rec.
           |   |__dicarboxylate:phosphate antiporter activity
           |   |__organophosphate:phosphate antiporter activity(+) 2 rec.
           |   |__oxalate:chloride antiporter activity
           |   |__sulfate:bicarbonate antiporter activity
           |   |__sulfate:chloride antiporter activity
           |__succinate:fumarate antiporter activity
           |__tartrate:succinate antiporter activity
           |__tetracycline:proton antiporter activity
           |__tyrosine:tyramine antiporter activity
           |__urate:monoatomic anion antiporter activity
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Is a secondary active transmembrane transporter activity
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Synonyms
  • "antiport" RELATED
    "countertransporter activity" EXACT
    "exchange transporter activity" EXACT
    "exchanger" BROAD
    "ion antiporter activity" NARROW
    "porter" BROAD
    "solute:solute antiporter activity" EXACT
    "solute:solute exchange" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-2730692 "CLCN4/5/6 exchange Cl- for H+"
Reactome:R-HSA-2730959 "CLCN7:OSTM1 exchanges Cl- for H+"
Reactome:R-HSA-2731002 "CLCN3 exchanges Cl- for H+"