FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term phosphatase activity ID (Ontology) GO:0016791 (Gene Ontology)
Definition Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.
Also Known As "phosphoric monoester hydrolase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      64
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 phosphatase activity (all annotations which use CV term, excluding "NOT" statements)       3     64
     enables | phosphatase activity       --      64
 NOT | enables | phosphatase activity       --       8
Spanning Tree (Parents/Children)
Only view relationship:
  hydrolase activity, acting on ester bonds
   |__phosphoric ester hydrolase activity
       |__phosphatase activity  212 rec.
           |__2-carboxy-D-arabinitol-1-phosphatase activity
           |__2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
           |__2-phosphosulfolactate phosphatase activity
           |__3',5'-nucleotide bisphosphate phosphatase activity
           |__3-deoxy-manno-octulosonate-8-phosphatase activity
           |__3-phosphoglycerate phosphatase activity
           |__5'-deoxynucleotidase activity 1 rec.
           |__5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
           |__10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
           |__acid phosphatase activity 12 rec.
           |__acireductone synthase activity 1 rec.
           |__ADP-phosphoglycerate phosphatase activity
           |__alkaline phosphatase activity 14 rec.
           |__alkylacetylglycerophosphatase activity
           |__alpha-ribazole phosphatase activity
           |__bisphosphoglycerate 3-phosphatase activity 2 rec.
           |__carbohydrate phosphatase activity 6 rec.
           |   |__sugar-phosphatase activity(+) 5 rec.
           |__D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
           |__deoxynucleotide 3'-phosphatase activity
           |__dihydrosphingosine-1-phosphate phosphatase activity
           |__dolichyl-phosphatase activity
           |__ecdysteroid-phosphate phosphatase activity 1 rec.
           |__FMN hydrolase activity
           |__fructose-1-phosphatase activity
           |__glucosylglycerol 3-phosphatase activity
           |__glycerol-2-phosphatase activity
           |__guanidinodeoxy-scyllo-inositol-4-phosphatase activity
           |__histidinol-phosphatase activity
           |__inositol phosphate phosphatase activity 16 rec.
           |   |__inositol bisphosphate phosphatase activity(+) 1 rec.
           |   |__inositol hexakisphosphate phosphatase activity(+)
           |   |__inositol monophosphate phosphatase activity(+) 6 rec.
           |   |__inositol pentakisphosphate phosphatase activity(+)
           |   |__inositol tetrakisphosphate phosphatase activity(+) 1 rec.
           |   |__inositol trisphosphate phosphatase activity(+) 4 rec.
           |__L-phosphoserine phosphatase activity 1 rec.
           |__lipid phosphatase activity 11 rec.
           |   |__ceramide-1-phosphate phosphatase activity
           |   |__phosphatidate phosphatase activity 9 rec.
           |   |__sphingosine-1-phosphate phosphatase activity 1 rec.
           |__lysophosphatidic acid phosphatase activity 1 rec.
           |__mannitol-1-phosphatase activity
           |__mannosyl-3-phosphoglycerate phosphatase activity
           |__methylphosphothioglycerate phosphatase activity
           |__monoterpenyl-diphosphatase activity
           |__N-acylneuraminate-9-phosphatase activity 1 rec.
           |__NADP phosphatase activity 1 rec.
           |__NADPH phosphatase activity 1 rec.
           |__nucleotidase activity 8 rec.
           |   |__3'(2'),5'-bisphosphate nucleotidase activity 1 rec.
           |   |__3'-nucleotidase activity 1 rec.
           |   |__5'-nucleotidase activity 5 rec.
           |__phosphatidylglycerophosphatase activity 1 rec.
           |__phosphatidylinositol phosphate phosphatase activity 17 rec.
           |   |__phosphatidylinositol bisphosphate phosphatase activity(+) 12 rec.
           |   |__phosphatidylinositol monophosphate phosphatase activity(+) 8 rec.
           |   |__phosphatidylinositol phosphate 4-phosphatase activity(+) 5 rec.
           |   |__phosphatidylinositol phosphate 5-phosphatase activity(+) 7 rec.
           |   |__phosphatidylinositol trisphosphate phosphatase activity(+) 3 rec.
           |__phosphocholine phosphatase activity
           |__phosphoenolpyruvate phosphatase activity
           |__phosphoethanolamine phosphatase activity
           |__phosphoglycerate phosphatase activity
           |__phosphoglycolate phosphatase activity
           |__phosphoprotein phosphatase activity 109 rec.
           |   |__[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity
           |   |__[acetyl-CoA carboxylase]-phosphatase activity
           |   |__[glycogen-synthase-D] phosphatase activity
           |   |__[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity
           |   |__[isocitrate dehydrogenase (NADP+)] phosphatase activity
           |   |__[phosphorylase] phosphatase activity
           |   |__[pyruvate kinase]-phosphatase activity
           |   |__histone phosphatase activity(+)
           |   |__MAP kinase phosphatase activity(+) 5 rec.
           |   |__myosin-light-chain-phosphatase activity
           |   |__protein arginine phosphatase activity 2 rec.
           |   |__protein histidine phosphatase activity 5 rec.
           |   |__protein serine/threonine phosphatase activity(+) 62 rec.
           |   |__protein tyrosine phosphatase activity(+) 30 rec.
           |   |__protein tyrosine/serine/threonine phosphatase activity(+) 14 rec.
           |   |__protein tyrosine/threonine phosphatase activity 2 rec.
           |   |__transmembrane receptor protein phosphatase activity(+) 8 rec.
           |__polynucleotide 3'-phosphatase activity 1 rec.
           |__polynucleotide 5'-phosphatase activity 1 rec.
           |__pseudouridine 5'-phosphatase activity 6 rec.
           |__pyridoxal phosphatase activity
           |__ribitol-5-phosphatase activity
           |__RNA 2',3'-cyclic phosphatase activity 1 rec.
           |__RNA 2'-phosphatase activity 1 rec.
           |__sedoheptulose-bisphosphatase activity
           |__sn-glycerol 1-phosphatase activity
           |__sn-glycerol 3-phosphatase activity 1 rec.
           |__sorbitol-6-phosphatase activity
           |__streptomycin-6-phosphatase activity
           |__thiamine phosphate phosphatase activity
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Is a phosphoric ester hydrolase activity
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Synonyms
  • "phosphatase" RELATED
    "phosphoric monoester hydrolase activity" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
EC:3.1.3.-
Reactome:R-HSA-4419986 "Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL"
Reactome:R-HSA-9636457 "SapM dephosphorylates PI3P"
Reactome:R-HSA-9837419 "PANK4 hydrolyzes PPANT to pantetheine"