FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term flippase activity ID (Ontology) GO:0140327 (Gene Ontology)
Definition Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.[ PubMed:20043909 PubMed:25284293 ]
Also Known As "flippase activity (exoplasmic to cytosolic leaflet)"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 flippase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | flippase activity       --
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intramembrane lipid carrier activity__
ATP-dependent activity________________|
                                      ATPase-coupled intramembrane lipid carrier activity
                                       |__flippase activity  3 rec.
                                           |__aminophospholipid flippase activity
                                           |   |__phosphatidylserine flippase activity
                                           |__glycerophospholipid flippase activity
                                           |   |__lysophosphatidylcholine flippase activity
                                           |   |__lysophosphatidylserine flippase activity
                                           |   |__phosphatidylcholine flippase activity
                                           |   |__phosphatidylethanolamine flippase activity
                                           |   |__phosphatidylserine flippase activity
                                           |__glycosylceramide flippase activity
                                           |__N-retinylidene-phosphatidylethanolamine flippase activity
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Is a ATPase-coupled intramembrane lipid carrier activity
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Synonyms
  • "flippase activity (exoplasmic to cytosolic leaflet)" EXACT
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