FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term flippase activity ID (Ontology) GO:0140327 (Gene Ontology)
Definition Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.[ PubMed:20043909 PubMed:25284293 ]
Also Known As "flippase activity (exoplasmic to cytosolic leaflet)"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 flippase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | flippase activity       --       2
Spanning Tree (Parents/Children)
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intramembrane lipid transporter activity__
ATP-dependent activity____________________|
                                          ATPase-coupled intramembrane lipid transporter activity
                                           |__flippase activity  4 rec.
                                               |__aminophospholipid flippase activity 1 rec.
                                               |   |__phosphatidylserine flippase activity
                                               |__glycerophospholipid flippase activity
                                               |   |__lysophosphatidylcholine flippase activity
                                               |   |__lysophosphatidylserine flippase activity
                                               |   |__phosphatidylcholine flippase activity
                                               |   |__phosphatidylethanolamine flippase activity
                                               |   |__phosphatidylserine flippase activity
                                               |__glycosylceramide flippase activity
                                               |__N-retinylidene-phosphatidylethanolamine flippase activity
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Is a ATPase-coupled intramembrane lipid transporter activity
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Synonyms
  • "flippase activity (exoplasmic to cytosolic leaflet)" EXACT
Secondary IDs
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