FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)66C-T2-10
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General Information
Symbol
Df(3L)66C-T2-10
Species
D. melanogaster
Name
FlyBase ID
FBab0037752
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 67C7--67C10
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{white-un2}30
(Harris et al., 2003)
Mutagen
X ray
(Harris et al., 2003)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Harris et al., 2003)
Breakpoints

67C7-67C10;67C7-67C10

(Harris et al., 2003)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Cbl
(Harris et al., 2003)
mtrm
(Bonner et al., 2013)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    FM7/X females heterozygous for Df(3L)66C-T2-10 show 30.9% X and 19.7% fourth chromosome nondisjunction.

    The primary cytological defect in heterozygous oocytes is malorientation of the nonexchange fourth chromosomes. The majority of spindles appear structurally normal.

    (Bonner et al., 2013)

    Heterozygosity for Df(3L)66C-T2-10 results in 39.2% X chromosome nondisjunction and 27.7% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females. The level of X chromosome nondisjunction in heterozygous Df(3L)66C-T2-10 females carrying two normal sequence X chromosomes is only 4.0%, while the frequency of fourth chromosome nondisjunction in these females is 42.1%. Achiasmate X and fourth chromosomes are often improperly placed on metaphase I spindles of oocytes in In(1)FM7/X ; Df(3L)66C-T2-10/+ females; achiasmate X chromosomes are found on the same half-spindle 21% of the time and fourth chromosomes are found on the same half-spindle 31% of the time.

    (Harris et al., 2003)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(3L)66C-T2-10
    (Bonner and Hawley, 2019, Bonner et al., 2013)
    Df(3L)T2-10
    (Harris et al., 2003)
    Name Synonyms
    Secondary FlyBase IDs
      References (4)