FB2025_01 , released February 20, 2025
Allele: Dmel\srp01549
Open Close
General Information
Symbol
Dmel\srp01549
Species
D. melanogaster
Name
FlyBase ID
FBal0009417
Feature type
allele
Associated gene
Dmel\srp
Associated Insertion(s)
P{PZ}srp01549
Carried in Construct
Also Known As
srpPZ
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Rehorn et al., 1996)
Mutagen
P-element activity
(Rehorn et al., 1996)
Progenitor genotype
Associated Insertion(s)
P{PZ}srp01549
Cytology
Description

P{PZ} insertion 30bp 5' of the putative transcription start site.

(Rehorn et al., 1996)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The average number of crystal cells per embryo is reduced (to 1) in homozygous stage 13-14 embryos compared to wild type (36 +/- 2.2 cells on average). The number of plasmatocytes is also significantly reduced compared to wild-type embryos.

      (Milchanowski et al., 2004)

      Germline clones produce eggs with patterning defects: tail region remains on dorsal side.

      (Perrimon et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      srpneo45

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: l(3)0520300934. Complements: Akt104226. Complements: l(3)0520308235. Complements: l(3)neo461. Complements: l(3)neo471.

      (BDGP Project Members, 1994-1999)

      Mobilisation of the P{PZ} element causes complete reversion of the lethal phenotype demonstrating the insertion to be responsible for the mutant phenotype.

      (Rehorn et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      Ins(3R)PZ1549
      P11538
      (Milchanowski et al., 2004)
      l(3)01549
      (Spradling et al., 1999)
      l(3)0154901549
      srp01549
      (Lei et al., 2023, Tokusumi et al., 2012)
      srpPZ01549
      (Hof-Michel et al., 2024)
      srpPZ
      (Hof-Michel et al., 2024, Lamka and Lipshitz, 1999, Rehorn et al., 1996)
      Name Synonyms
      Secondary FlyBase IDs
        References (14)