FB2025_01 , released February 20, 2025
Allele: Dmel\Polr2A27
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General Information
Symbol
Dmel\Polr2A27
Species
D. melanogaster
Name
FlyBase ID
FBal0014684
Feature type
allele
Associated gene
Dmel\Polr2A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Voelker et al., 1985)
Progenitor genotype
Polr2A4
(Voelker et al., 1985)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies show resistance to α-amanitin. Homozygous males are partially fertile.

      (Voelker et al., 1985)

      retains α-amanitin resistance.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Polr2A27 has phenotype, enhanceable by Polr2BS1

      (Krasnoselskaya et al., 1998)

      Polr2A27 has phenotype, enhanceable by Polr2BS8

      (Krasnoselskaya et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Reduced viability in combination with RpII140S1 or RpII140S8.

      (Krasnoselskaya et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      F90
      (Voelker et al., 1985)
      Polr2A27
      RpII21527
      RpII215F90
      Name Synonyms
      Secondary FlyBase IDs
        References (2)