FlyBase Allele Report: Dmel\stmA[p1]

General Information

Symbol

Dmel\stmA^p1

Species

D. melanogaster

Name

FlyBase ID

FBal0051085

Feature type

allele

Associated gene

Dmel\stmA

Associated Insertion(s)

P{}stmA^p1

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Kumar et al., 2001, Chandrashekaran, 1993)

Progenitor genotype

Associated Insertion(s)

P{}stmA^p1

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal flight

(Kumar et al., 2001)

abnormal locomotor behavior | adult stage

(Kumar et al., 2001)

chemical resistant

(Chandrashekaran, 1993)

decreased rate of movement

(Kumar et al., 2001)

lethal | recessive

(Kumar et al., 2001)

paralytic | heat sensitive

(Rao et al., 2001, Chandrashekaran, 1993)

paralytic | heat sensitive (with Df(2R)H3C1)

(Rao et al., 2001)

paralytic | heat sensitive (with Df(2R)H3E1)

(Rao et al., 2001)

paralytic | heat sensitive (with stmA¹)

(Kumar et al., 2001)

viable

(Chandrashekaran, 1993)

Phenotype Manifest In

Detailed Description

Statement

Reference

Paralysis at 38^oC over stmA¹ and recovery at 24^oC. stmA^p1 is hypoactive at 24^oC and weakly negatively geotactic. Adults are almost always flightless.

(Kumar et al., 2001)

Adult males are resistant to the lethal effects of the sodium channel neuropoison veratridine.

(Chandrashekaran, 1993)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

stmA^1-4

(Kumar et al., 2001)

stmA^27-1

(Kumar et al., 2001)

Fails to complement

stmA^1-2

(Kumar et al., 2001)

stmA^18-2

(Kumar et al., 2001)

stmA^KP2

(Kumar et al., 2001)

stmA^KP4

(Kumar et al., 2001)

stmA¹

(Kumar et al., 2001)

stmA¹²

(Kumar et al., 2001)

stmA²

(Kumar et al., 2001)

stmA⁷

(Kumar et al., 2001)

stmA^p4

(Kumar et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Wild-type revertants have not been recovered in a screen to remobilise the P-elements present in the stmA^p1 strain (3414 chromosomes tested). 6 recessive lethal excision events have been recovered in 557 chromosomes tested.

(Rao et al., 2001)

Group III allele.

(Kumar et al., 2001)

Allelic series for the paralytic phenotype: stmA² > stmA^p1 > stmA¹ > stmA^p2 > stmA^p4.

(Chandrashekaran, 1993)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

stmA^P1

(Kumar et al., 2001, Rao et al., 2001)

stmA^p1

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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