FB2025_01 , released February 20, 2025
Allele: Dmel\Rh6ninaE.PS
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General Information
Symbol
Dmel\Rh6ninaE.PS
Species
D. melanogaster
Name
neither inactivation nor afterpotential E promoter construct of Salcedo
FlyBase ID
FBal0104007
Feature type
allele
Associated gene
Dmel\Rh6
Associated Insertion(s)
Carried in Construct
P{Rh1+6}
Key Links
Transgenic product class
cDNA
(Salcedo et al., 1999)
wild_type
(Salcedo et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Salcedo et al., 1999)
wild_type
(Salcedo et al., 1999)
Mutagen
in vitro construct
(Salcedo et al., 1999)
Progenitor genotype
Carried in construct
P{Rh1+6}
Cytology
Description

A 1.4kb Rh6 cDNA fragment (containing the entire coding region and poly A tail) is expressed under the control of a 2.4kb ninaE promoter fragment (which includes 33bp of the 5' untranslated region).

(Salcedo et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
Rh6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Rh6ninaE.PS is a suppressor of phenotype of ninaE17

      (Salcedo et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Rh6ninaE.PS rescues the ability of ninaE17 larvae to strongly discriminate between 18[o]C and 24[o]C in a binary choice thermotaxis assay.

      (Shen et al., 2011)

      The electroretinograms of homozygous ninaE17 flies have no on- or off-transients and the magnitude of depolarisation is dramatically reduced compared to wild-type. The light response in the ERG is completely restored if the flies are carrying Rh6ninaE.PS.

      (Salcedo et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rh6ninaE.PS
      Name Synonyms
      neither inactivation nor afterpotential E promoter construct of Salcedo
      (Salcedo et al., 1999)
      Secondary FlyBase IDs
        References (2)