FB2025_01 , released February 20, 2025
Allele: Dmel\Tak1unspecified
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General Information
Symbol
Dmel\Tak1unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0126471
Feature type
allele
Associated gene
Dmel\Tak1
Associated Insertion(s)
Carried in Construct
Also Known As
dtak1
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygotes have no apparent tissue polarity defects.

        (Stronach and Perrimon, 2002)

        Mutant flies are weakly susceptible to Gram-negative bacterial infection and resistant to Gram-positive bacterial and fungal infection.

        (Vidal et al., 2001)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        NOT Suppressor of
        Statement
        Reference

        Tak1unspecified is a non-suppressor of visible phenotype of Scer\GAL4GMR.PF, hepCA.UAS

        (Geuking et al., 2005)
        Phenotype Manifest In
        Suppressor of
        NOT Suppressor of
        Statement
        Reference

        Tak1unspecified is a non-suppressor of eye phenotype of Scer\GAL4GMR.PF, hepCA.UAS

        (Geuking et al., 2005)
        Other
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Tak1unspecified/+ partially suppresses the lethal dorsal open phenotype of Scer\GAL4pnr-MD237>POSHScer\UAS.cSa. Escapees survive to adulthood with thorax defects.

        (Zhang et al., 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Tak1unspecified is rescued by Tak1+t15

        (Vidal et al., 2001)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Tak1unspecified
        dtak1
        (Radyuk et al., 2010, Zhang et al., 2010)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)