Allele Dmel\Pen^Scer\UAS.cMa

General Information
Symbol	Dmel\Pen^Scer\UAS.cMa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Mason	FlyBase ID	FBal0137396
Feature type	allele	Associated gene	Dmel\Pen

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Mason et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\UAS regulatory sequences drive expression of Pen. (Mason et al., 2002)
Carried in construct	P{UAS-Pen.M} (Mason et al., 2002, Ratan et al., 2008, Mosca and Schwarz, 2010)
Cytology
Phenotypic Data
Phenotypic Class
	viable, with Scer\GAL4^e22c (Ratan et al., 2008)
Phenotype Manifest In

Detailed Description
	Statement Reference Expression of Pen[Scer\UAS.cMa] under the control of Scer\GAL4[e22c] does not result in lethality or defects in the adult abdomen. (Ratan et al., 2008)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^how-24B, Scer\GAL4^how-24B, Pen^Scer\UAS.cMa rescues Pen^D14 (Mosca and Schwarz, 2010)
Partially rescues	Pen^Scer\UAS.cMa/Scer\GAL4^hs.PB partially rescues Pen^D14 (Mason et al., 2002)
Fails to rescue	Scer\GAL4^elav.PLu/Pen^Scer\UAS.cMa fails to rescue Pen^D14 (Mosca and Schwarz, 2010)
Comments	Expression of Pen[Scer\UAS.cMa] under the control of Scer\GAL4[how-24B] largely rescues the somatic muscle patterning defects seen in Pen[D14] larvae. Expression of Pen[Scer\UAS.cMa] under the control of Scer\GAL4[elav.PLu] does not rescue the somatic muscle patterning defects seen in Pen[D14] larvae. (Mosca and Schwarz, 2010) Expression of Pen^Scer\UAS.cMa under the control of Scer\GAL4^hs.PB using heat shock partially rescues the sterility of Pen^D14 males. (Mason et al., 2002)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Pen^Scer\UAS.cMa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Mason (Mason et al., 2002)
Secondary FlyBase IDs

References ( 3 )
Research paper	Mosca and Schwarz, 2010, PLoS ONE 5(12): e15223 Drosophila Importin-α2 Is Involved in Synapse, Axon and Muscle Development. [FBrf0212532] Ratan et al., 2008, Genetics 178(2): 839--850 Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis. [FBrf0204254] Mason et al., 2002, Genetics 161(1): 157--170 Drosophila melanogaster importin alpha1 and alpha3 can replace importin alpha2 during spermatogenesis but not oogenesis. [FBrf0149010]

Allele Dmel\PenScer\UAS.cMa

Allele Dmel\Pen^Scer\UAS.cMa