FB2025_01 , released February 20, 2025
Allele: Dmel\smoSD123.UAS.CFP
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General Information
Symbol
Dmel\smoSD123.UAS.CFP
Species
D. melanogaster
Name
FlyBase ID
FBal0175476
Feature type
allele
Associated gene
Dmel\smo
Associated Insertion(s)
Carried in Construct
P{UAS-smo.CFP.SD123}
PBac{UAS-smo.CFP.SD123}
Also Known As
SmoSD123, UAS-SmoSD123-CFP
Key Links
Transgenic product class
missense_variant
(Jia et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Jia et al., 2004)
Mutagen
in vitro construct
(Chen et al., 2010, Jia et al., 2004)
Progenitor genotype
smoC.UAS.CFP
(Jia et al., 2004)
Carried in construct
P{UAS-smo.CFP.SD123}
PBac{UAS-smo.CFP.SD123}
Cytology
Description

UAS regulatory sequences drive expression of smo which carries phospho-mimetic mutations in the three PKA/CK1 phosphorylation sites (SD123). The protein is tagged with CFP.

(Chen et al., 2010)

Construct: Amino acid replacement: S670D. Amino acid replacement: S673D. Amino acid replacement: S667D. Amino acid replacement: S687D. Amino acid replacement: S680D. Amino acid replacement: S683D. Amino acid replacement: S740D. Amino acid replacement: S743D. Amino acid replacement: S746D.

(Jia et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
smo
Tagged with
CFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells.

      (Jia et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SmoSD123
      (Xia et al., 2012)
      smoSD123.Scer\UAS.T:Avic\GFP-CFP
      smoSD123.UAS.CFP
      Name Synonyms
      Secondary FlyBase IDs
        References (7)