FB2025_01 , released February 20, 2025
Allele: Dmel\Tdc1UAS.cCa
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General Information
Symbol
Dmel\Tdc1UAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Cole
FlyBase ID
FBal0191665
Feature type
allele
Associated gene
Dmel\Tdc1
Associated Insertion(s)
Carried in Construct
P{UAS-Tdc1.C}
Also Known As
UAS-Tdc1
Key Links
Transgenic product class
wild_type
(Cole et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Cole et al., 2005)
Mutagen
in vitro construct
(Cole et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Tdc1.C}
Cytology
Description

UASt regulatory sequences drive expression of the Tdc1 coding region.

(Cole et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tdc1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Tdc2.PC/Tdc1UAS.cCa is a non-suppressor of adult brain phenotype of Tdc2RO54

      (Cole et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Tdc1Scer\UAS.cCa under the control of Scer\GAL4Tdc2.PC results in complete suppression of the cocaine sensitivity phenotype of Tdc2RO54 flies.

      (Hardie et al., 2007)

      Expression of Tdc1Scer\UAS.cCa, under the control of Scer\GAL4Tdc2.PC, completely rescues the egg retention phenotype of Tdc2RO54 mutants. However, expression of this transgene fails to rescue the reduced neural tyramine and octopamine phenotype.

      (Cole et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Tdc1Scer\UAS.cCa
      Tdc1UAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Cole
      (Cole et al., 2005)
      Secondary FlyBase IDs
        References (3)