FB2025_01 , released February 20, 2025
Allele: Dmel\tayUAS.cPa
Open Close
General Information
Symbol
Dmel\tayUAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Poeck
FlyBase ID
FBal0220494
Feature type
allele
Associated gene
Dmel\tay
Associated Insertion(s)
Carried in Construct
P{UAS-tay.P}
Key Links
Transgenic product class
cDNA
(Poeck et al., 2008)
wild_type
(Poeck et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Poeck et al., 2008)
wild_type
(Poeck et al., 2008)
Mutagen
in vitro construct
(Poeck et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-tay.P}
Cytology
Description

Expression of tay cDNA (LD22609) is under the control of UASt sequences.

(Poeck et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tay
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4007Y/tayUAS.cPa rescues tay1

      (Poeck et al., 2008)
      Fails to rescue

      tayUAS.cPa/Scer\GAL4elav.PLu fails to rescue tay1

      (Poeck et al., 2008)

      Scer\GAL4210Y/tayUAS.cPa fails to rescue tay1

      (Poeck et al., 2008)
      Comments

      tayScer\UAS.cPa with Scer\GAL4elav.PLu does not rescue the protocerebral bridge defects seen in tay1 homozygotes, and only weakly rescues their locomotor defects. When Scer\GAL4210Y. Scer\GAL4Aph-4-c232, Scer\GAL4c819, Scer\GAL4NP2320 or Scer\GAL4NP3124 is instead used as a driver, no rescue of protocerebral bridge or locomotor defects is seen. In contrast, when Scer\GAL4007Y is used as a driver, both protocerebral and locomotor defects are completely rescued. When Scer\GAL4Mef2.247 is used as driver, the protocerebral bridge defects are not rescued but some locomotor defects are: walking activity (in Buridan's paradigm) is partially rescued; optomotor compensation is fully rescued; walking speed is not rescued.

      (Poeck et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tayScer\UAS.cPa
      tayUAS.cPa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Poeck
      Secondary FlyBase IDs
        References (1)