FB2025_01 , released February 20, 2025
Allele: Dmel\Stat92EM647H.UAS.EGFP
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General Information
Symbol
Dmel\Stat92EM647H.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0260717
Feature type
allele
Associated gene
Dmel\Stat92E
Associated Insertion(s)
Carried in Construct
P{UAS-Stat92E.EGFP.M647H}
Key Links
Transgenic product class
dominant_negative_variant
(Karsten et al., 2006)
missense_variant
(Karsten et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
dominant_negative_variant
(Karsten et al., 2006)
missense_variant
(Karsten et al., 2006)
Mutagen
in vitro construct
(Karsten et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Stat92E.EGFP.M647H}
Cytology
Description

Amino acid replacement: M647H.

(Karsten et al., 2006)

Dominant negative allele.

(Karsten et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Stat92E
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Stat92EM647H.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4Mef2.247.Switch specifically during the adult stage (in the presence of RU486) causes a striking defect in long term memory, without affecting anesthesia-resistant memory or short term memory.

      (Copf et al., 2011)

      Expression of Stat92EM647H.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4ey.PU results in roughening of the eye, a reduction in eye volume and a loss of ventral eye tissue.

      (Karsten et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Stat92EM647H.Scer\UAS.T:Avic\GFP-EGFP
      Stat92EM647H.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)