FlyBase Allele Report: Dmel\Ctdnep1[UAS.cLa]

General Information

Symbol

Dmel\Ctdnep1^UAS.cLa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Liu

FlyBase ID

FBal0263645

Feature type

allele

Associated gene

Dmel\Ctdnep1

Associated Insertion(s)

Carried in Construct

P{UAS-Ctdnep1.L}

Key Links

Transgenic product class

cDNA

(Liu et al., 2011)

wild_type

(Liu et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Liu et al., 2011)

wild_type

(Liu et al., 2011)

Mutagen

in vitro construct

(Liu et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-Ctdnep1.L}

Cytology

Description

UAS drives expression of the LD04380 Dd cDNA.

(Liu et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ctdnep1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

anterior crossvein, with Scer\GAL4^dpp.blk1

(Liu et al., 2011)

anterior crossvein, with Scer\GAL4^en-e16E

(Liu et al., 2011)

anterior crossvein | heat sensitive, with Scer\GAL4^71B

(Liu et al., 2011)

endoplasmic reticulum, with Scer\GAL4^en-e16E

(Liu et al., 2011)

lipid droplet, with Scer\GAL4^en-e16E

(Liu et al., 2011)

posterior crossvein, with Scer\GAL4^en-e16E

(Liu et al., 2011)

posterior crossvein | heat sensitive, with Scer\GAL4^71B

(Liu et al., 2011)

wing vein L4, with Scer\GAL4^en-e16E

(Liu et al., 2011)

wing vein L5, with Scer\GAL4^en-e16E

(Liu et al., 2011)

Detailed Description

Statement

Reference

Expression of Dd^Scer\UAS.cLa with Scer\GAL4^dpp.blk1 dramatically suppresses formation of the anterior crossvein.

Expression of Dd^Scer\UAS.cLa with Scer\GAL4^71B at 29[o]C suppresses formation of both or either of the anterior and posterior crossveins.

Expression of Dd^Scer\UAS.cLa with Scer\GAL4^en-e16E alters the overall shape of the posterior half of the wing blade, suppresses formation of the anterior crossvein, and partially suppresses formation of the posterior crossvein and veins L4 and L5.

Scer\GAL4^en-e16E-mediated expression of Dd^Scer\UAS.cLa disrupts endoplasmic reticulum morphology and increases the size of fat droplets within wing imaginal discs.

(Liu et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Ctdnep1^UAS.cLa/Scer\GAL4^hs.PU rescues Ctdnep1^G0269

(Liu et al., 2011)

Comments

Scer\GAL4^hs.PU-mediated expression of Dd^Scer\UAS.cLa rescues the abnormal vein phenotypes of Dd^G0269.

(Liu et al., 2011)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ctdnep1^UAS.cLa

Dd^Scer\UAS.cLa

Dd^UAS.cLa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Liu

Secondary FlyBase IDs

References (1)

Report Sections

Open Close