FB2025_01 , released February 20, 2025
Allele: Dmel\MtnAUAS.cHa
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General Information
Symbol
Dmel\MtnAUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hua
FlyBase ID
FBal0264197
Feature type
allele
Associated gene
Dmel\MtnA
Associated Insertion(s)
Carried in Construct
P{UAS-MtnA.H}
Key Links
Transgenic product class
wild_type
(Hua et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hua et al., 2011)
Mutagen
in vitro construct
(Hua et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-MtnA.H}
Cytology
Description

UAS regulatory sequences drive expression of MtnA.

(Hua et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
MtnA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease
      modeled by Hsap\APPAβ42.UAS.Tag:SS(hh)
      (Hua et al., 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      MtnAUAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Hsap\APPAβ42.UAS.Tag:SS(hh), Scer\GAL4GMR.PF

      (Hua et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of MtnAScer\UAS.cHa with Hsap\APPAβ42.Scer\UAS.T:hh under the control of Scer\GAL4GMR.PF ameliorates the eye phenotype caused by Hsap\APPAβ42.Scer\UAS.T:hh expression alone.

      (Hua et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      MtnAScer\UAS.cHa
      MtnAUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hua
      Secondary FlyBase IDs
        References (1)