FB2025_01 , released February 20, 2025
Allele: Dmel\AP-2αΔEar5.UAS.GFP
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General Information
Symbol
Dmel\AP-2αΔEar5.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0270127
Feature type
allele
Associated gene
Dmel\AP-2α
Associated Insertion(s)
Carried in Construct
P{UAS-AP-2α.GFP.ΔEar5}
Key Links
Transgenic product class
inframe_deletion
(Song and Lu, 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Song and Lu, 2012)
Mutagen
in vitro construct
(Song and Lu, 2012)
Progenitor genotype
Carried in construct
P{UAS-AP-2α.GFP.ΔEar5}
Cytology
Description

UASt regulatory sequences drive expression of a GFP-tagged and truncated AP-2α polypeptide lacking the C-terminal half of the 'EAR' domain.

(Song and Lu, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
AP-2α
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4insc-Mz1407/AP-2αΔEar5.UAS.GFP rescues AP-2α06694

      (Song and Lu, 2012)

      Scer\GAL4insc-Mz1407/AP-2αΔEar5.UAS.GFP rescues AP-2αSH0460

      (Song and Lu, 2012)
      Comments

      Neuroblast-specific expression of α-AdaptinΔEar5.Scer\UAS.T:Avic\GFP via Scer\GAL4insc-Mz1407 completely rescues the neuroblast overproliferation phenotype of α-AdaptinSH0460 and α-Adaptin06694 mutants.

      (Song and Lu, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      AP-2αΔEar5.Scer\UAS.T:Avic\GFP
      AP-2αΔEar5.UAS.GFP
      α-AdaptinΔEar5.Scer\UAS.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)