FB2025_01 , released February 20, 2025
Allele: Dmel\Prx2UASp.cDa
Open Close
General Information
Symbol
Dmel\Prx2UASp.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0280981
Feature type
allele
Associated gene
Dmel\Prx2
Associated Insertion(s)
Carried in Construct
P{UASp-Prx2.D}
Key Links
Transgenic product class
wild_type
(Degennaro et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Degennaro et al., 2011)
Mutagen
in vitro construct
(Degennaro et al., 2011)
Progenitor genotype
Carried in construct
P{UASp-Prx2.D}
Cytology
Description

UASp regulatory sequences drive expression of a full-length Jafrac1 open reading frame.

(Degennaro et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Prx2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Jafrac1Scer\UAS.P\T.cDa under the control of the RU4856-inducible Scer\GAL4αTub84B.Switch.PK system is sufficient to enhance resistance to oxidative stress.

      (Degennaro et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Prx2UASp.cDa/Scer\GAL4Act5C.PI rescues Prx2KG05372

      (Degennaro et al., 2011)
      Comments

      Ubiquitous expression of Jafrac1Scer\UAS.P\T.cDa under the control of Scer\GAL4Act5C.PI rescues the paraquat sensitivity found in Jafrac1KG05372 mutants.

      (Degennaro et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Jafrac1Scer\UAS.P\T.cDa
      Jafrac1UASp.cDa
      Prx2UASp.cDa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)