FB2025_01 , released February 20, 2025
Allele: Dmel\Ae2HMC03399
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General Information
Symbol
Dmel\Ae2HMC03399
Species
D. melanogaster
Name
FlyBase ID
FBal0292548
Feature type
allele
Associated gene
Dmel\Ae2
Associated Insertion(s)
Carried in Construct
P{TRiP.HMC03399}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
in vitro construct
(Ni et al., 2010.12.1)
Progenitor genotype
Carried in construct
P{TRiP.HMC03399}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMC03399
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing CG8177HMC03399 under the control of Scer\GAL4fkh.PH does not significantly affect the clearing of salivary gland tissue in pupae, as compared to controls.

      (Velentzas et al., 2018)

      Expression of CG8177HMC03399 under the control of Scer\GAL4Tsp42Ec leads to reduced acidity in the acidic region of the larval midgut, as compared with controls.

      (Overend et al., 2016)

      The expression of CG8177HMC03399 under the control of Scer\GAL4109-30 leads to ovarioles frequently exhibiting multilayered stalks and leads to a significant increase in intracellular pH in follicle stem cells, pre-follicle and follicle cells within the germarium, as compared to controls.

      (Ulmschneider et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Ae2HMC03399, Scer\GAL4GMR.long is a non-suppressor of eye phenotype of Scer\GAL4GMR.long, Zzzz\GGGGCC30.UAS.EGFP

      (Jiao et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ae2HMC03399
      CG8177HMC03399
      CG8177TRIP
      (Ulmschneider et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)