FB2025_01 , released February 20, 2025
Allele: Dmel\DCP2UAS.cRa
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General Information
Symbol
Dmel\DCP2UAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ren
FlyBase ID
FBal0320391
Feature type
allele
Associated gene
Dmel\DCP2
Associated Insertion(s)
Carried in Construct
P{UAS-DCP2.R}
Also Known As
UAS-Dcp2
Key Links
Transgenic product class
cDNA
(Ren et al., 2012)
wild_type
(Ren et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ren et al., 2012)
wild_type
(Ren et al., 2012)
Mutagen
in vitro construct
(Ren et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-DCP2.R}
Cytology
Description

UASt regulatory sequences drive expression of a full-length DCP2 cDNA.

(Ren et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
DCP2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of DCP2Scer\UAS.cRa under the control of Scer\GAL4elav.PU confers resistance to chronic nicotine-induced locomotor hyperactivity, but does not affect basal locomotor activity without nicotine treatment, as compared to controls.

      (Ren et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      DCP2UAS.cRa/Scer\GAL4Act5C.PI partially rescues DCP2tb

      (Mishra et al., 2020)

      DCP2UAS.cRa/Scer\GAL4Tub.PU partially rescues DCP2tb

      (Mishra et al., 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DCP2Scer\UAS.cRa
      DCP2UAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ren
      Secondary FlyBase IDs
        References (2)