FlyBase Allele Report: Dmel\Ilp6[UAS.cUa]

General Information

Symbol

Dmel\Ilp6^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0325720

Feature type

allele

Associated gene

Dmel\Ilp6

Associated Insertion(s)

Carried in Construct

P{UAS-Ilp6.U}

Key Links

Transgenic product class

wild_type

(Aradhya et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Aradhya et al., 2015)

Mutagen

in vitro construct

(Aradhya et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Ilp6.U}

Cytology

Description

UAS regulatory sequences drive expression of Ilp6.

(Aradhya et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ilp6

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | larval stage, with Scer\GAL4^repo.PU

(Harrison et al., 2021)

increased cell number | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

Phenotype Manifest In

abdominal dorsal adult muscle precursor cell | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

abdominal lateral adult muscle precursor cell | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

larval glial cell | increased number | larval stage, with Scer\GAL4^repo.PU

(Harrison et al., 2021)

larval ventral nerve cord, with Scer\GAL4^repo.PU

(Harrison et al., 2021)

Detailed Description

Statement

Reference

Expression of Ilp6^Scer\UAS.cUa under the control of Scer\GAL4^Mef2.PR leads to significantly increased numbers of abdominal lateral and dorsal, but not ventral, adult muscle precursor cells in third instar larvae, as compared to controls.

(Aradhya et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ilp6^UAS.cUa, Scer\GAL4^repo.PU has increased cell number | larval stage phenotype, suppressible by InR^K1409A.UAS, Scer\GAL4^repo.PU

(Harrison et al., 2021)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ilp6^UAS.cUa, Scer\GAL4^repo.PU has larval ventral nerve cord phenotype, suppressible by InR^K1409A.UAS, Scer\GAL4^repo.PU

(Harrison et al., 2021)

Ilp6^UAS.cUa, Scer\GAL4^repo.PU has larval glial cell | increased number | larval stage phenotype, suppressible by InR^K1409A.UAS, Scer\GAL4^repo.PU

(Harrison et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ilp6^Scer\UAS.cUa

Ilp6^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (3)

Report Sections

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