FlyBase Allele Report: Dmel\Coq2[RNAi.UAS.cUa]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\Coq2^RNAi.UAS.cUa

General Information

Symbol

Dmel\Coq2^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0376025

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-Coq2.RNAi.U}

Key Links

Transgenic product class

(Zhu et al., 2017)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Zhu et al., 2017)

Mutagen

in vitro construct

(Zhu et al., 2017)

Progenitor genotype

Carried in construct

P{UAS-Coq2.RNAi.U}

Cytology

Description

UAS regulates expression of an RNAi construct targeting Coq2.

(Zhu et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

autophagosome, with Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

mitochondrial crista, with Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

mitochondrion, with Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

nephrocyte, with Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

slit diaphragm, with Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Coq2^RNAi.UAS.cUa, Scer\GAL4^Ugt36A1.PK has nephrocyte phenotype, enhanceable by Atg1^JF02273, Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

Coq2^RNAi.UAS.cUa, Scer\GAL4^Ugt36A1.PK has nephrocyte phenotype, enhanceable by Atg6^JF02897, Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

Suppressed by

Statement

Reference

Coq2^RNAi.UAS.cUa, Scer\GAL4^Ugt36A1.PK has nephrocyte phenotype, suppressible by Hsap\COQ2^WT.UAS, Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

NOT suppressed by

Statement

Reference

Coq2^RNAi.UAS.cUa, Scer\GAL4^Ugt36A1.PK has nephrocyte phenotype, non-suppressible by Hsap\COQ2^S146N.UAS, Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

Enhancer of

Statement

Reference

Coq2^RNAi.UAS.cUa, Scer\GAL4^Ugt36A1.PK is an enhancer of nephrocyte phenotype of Atg6^JF02897, Scer\GAL4^Ugt36A1.PK

(Zhu et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Coq2^RNAi.UAS.cUa

Coq2^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections