FlyBase Allele Report: Dmel\Usp7[RNAi.UAS.II]

General Information

Symbol

Dmel\Usp7^RNAi.UAS.II

Species

D. melanogaster

Name

FlyBase ID

FBal0405289

Feature type

allele

Associated gene

Dmel\Usp7

Associated Insertion(s)

Carried in Construct

P{UAS-Usp7.RNAi.II}

Key Links

Transgenic product class

RNAi_reagent

(Lake et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Lake et al., 2024)

Mutagen

in vitro construct

(Lake et al., 2024)

Progenitor genotype

Carried in construct

P{UAS-Usp7.RNAi.II}

Cytology

Description

UAS regulatory sequences (from pVALIUM20) drive expression of a short hairpin repeat that targets the first exon of Usp7 (the hairpin contains an inverted repeat of CACGTGCCCGGATTAAGCATTTGTT).

(Lake et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Usp7

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Lake et al., 2024)

female semi-fertile, with Scer\GAL4^{VP16.mat.αTub67C}

(Lake et al., 2024)

female semi-fertile, with Scer\GAL4^{VP16.nanos.UTR}

(Lake et al., 2024)

male semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}

(Lake et al., 2024)

Phenotype Manifest In

synaptonemal complex | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Lake et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has abnormal meiotic cell cycle | oogenesis phenotype, non-enhanceable by vilya⁸²⁶/vilya⁸²⁶

(Lake et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has abnormal meiotic cell cycle | oogenesis phenotype, non-suppressible by vilya⁸²⁶/vilya⁸²⁶

(Lake et al., 2024)

Other

Statement

Reference

Df(3L)sina^SH/sina^A4, Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has abnormal meiotic cell cycle | oogenesis phenotype

(Lake et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has synaptonemal complex | oogenesis phenotype, non-enhanceable by vilya⁸²⁶/vilya⁸²⁶

(Lake et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has synaptonemal complex | oogenesis phenotype, non-suppressible by vilya⁸²⁶/vilya⁸²⁶

(Lake et al., 2024)

Other

Statement

Reference

Df(3L)sina^SH/sina^A4, Scer\GAL4^{VP16.nanos.UTR}, Usp7^RNAi.UAS.II has synaptonemal complex | oogenesis phenotype

(Lake et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Usp7^RNAi.UAS.II

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close